# Analysis title: 72934_peaks analysis from Cistrome-GO # Mode: Solo mode # Specie: hg38 # Peak bed file name: 72934_peaks.bed # Top peaks to use: 10000 # Half-decay distance: 10000bp # FDR cutoff of GO/KEGG terms to return: 0.2 # Minimum and maximum gene number in GO and KEGG gene sets: 10, 2000 # Term N,n,B,b Erichment p_value FDR Gene_number Progesterone-mediated oocyte maturation(hsa04914) 7753, 117, 99, 5 3.347 0.124358089372 0.385099046882 99 Retinol metabolism(hsa00830) 7753, 651, 67, 4 0.711 0.983964690783 0.999994743672 67 MAPK signaling pathway(hsa04010) 7753, 206, 295, 17 2.169 0.028442071782 0.179753893662 295 Protein export(hsa03060) 7753, 828, 23, 4 1.628 0.539590963806 0.823723403684 23 Intestinal immune network for IgA production(hsa04672) 7753, 612, 47, 1 0.27 0.998570110996 0.999994743672 47 Leukocyte transendothelial migration(hsa04670) 7753, 131, 112, 9 4.756 0.00153968077087 0.0405449269662 112 Phenylalanine metabolism(hsa00360) 7753, 1305, 17, 4 1.398 0.608486537735 0.857611294787 17 AGE-RAGE signaling pathway in diabetic complications(hsa04933) 7753, 1883, 100, 40 1.647 0.00429528987613 0.0646338857551 100 Parathyroid hormone synthesis, secretion and action(hsa04928) 7753, 1941, 106, 41 1.545 0.0140157685843 0.119702239801 106 Cortisol synthesis and secretion(hsa04927) 7753, 1500, 65, 20 1.59 0.122158982857 0.385099046882 65 Relaxin signaling pathway(hsa04926) 7753, 523, 130, 16 1.825 0.106119731144 0.35298773728 130 Aldosterone synthesis and secretion(hsa04925) 7753, 1500, 98, 30 1.582 0.0431689174603 0.227356298624 98 Renin secretion(hsa04924) 7753, 1486, 69, 26 1.966 0.00293175897571 0.0617623890883 69 Regulation of lipolysis in adipocytes(hsa04923) 7753, 117, 54, 5 6.136 0.0114362430502 0.109510691026 54 Glucagon signaling pathway(hsa04922) 7753, 1074, 103, 24 1.682 0.0542957448167 0.239577712494 103 Oxytocin signaling pathway(hsa04921) 7753, 148, 153, 10 3.424 0.0088093564757 0.0927592071911 153 Adipocytokine signaling pathway(hsa04920) 7753, 49, 69, 3 6.879 0.0734785809407 0.283161360698 69 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis(hsa00563) 7753, 315, 25, 2 1.969 0.601057912469 0.857611294787 25 Inositol phosphate metabolism(hsa00562) 7753, 1268, 74, 17 1.405 0.378961008528 0.708589814762 74 Glycerolipid metabolism(hsa00561) 7753, 817, 61, 10 1.556 0.407509419717 0.742461122144 61 Circadian entrainment(hsa04713) 7753, 130, 97, 5 3.074 0.156217656872 0.419724664504 97 Ether lipid metabolism(hsa00565) 7753, 478, 46, 2 0.705 0.968166000782 0.999994743672 46 Glycerophospholipid metabolism(hsa00564) 7753, 1021, 96, 19 1.503 0.249083516102 0.562217079202 96 Ribosome biogenesis in eukaryotes(hsa03008) 7753, 983, 79, 11 1.098 0.842182349782 0.996014522543 79 Thermogenesis(hsa04714) 7753, 370, 218, 26 2.499 0.000266453274277 0.0120284620959 218 Endocrine resistance(hsa01522) 7753, 542, 96, 14 2.086 0.0553454842153 0.239577712494 96 Antifolate resistance(hsa01523) 7753, 340, 31, 2 1.471 0.751744159769 0.950204617948 31 Platinum drug resistance(hsa01524) 7753, 836, 73, 13 1.652 0.251767447195 0.564244775275 73 Herpes simplex virus 1 infection(hsa05168) 7753, 306, 490, 25 1.293 0.559081710021 0.837297726856 490 Epstein-Barr virus infection(hsa05169) 7753, 353, 199, 15 1.656 0.258578135642 0.575427400443 199 ECM-receptor interaction(hsa04512) 7753, 1078, 82, 20 1.754 0.0583790474117 0.249294310569 82 Influenza A(hsa05164) 7753, 10, 169, 2 9.175 0.145416877716 0.407674179397 169 Human papillomavirus infection(hsa05165) 7753, 150, 330, 13 2.036 0.113074504446 0.364607585765 330 Human T-cell leukemia virus 1 infection(hsa05166) 7753, 1158, 218, 44 1.351 0.162051357194 0.430321251037 218 Kaposi sarcoma-associated herpesvirus infection(hsa05167) 7753, 976, 186, 32 1.367 0.261426045547 0.577696716034 186 Hepatitis C(hsa05160) 7753, 542, 155, 22 2.03 0.0132493051593 0.119622298009 155 Hepatitis B(hsa05161) 7753, 887, 163, 29 1.555 0.087377512446 0.313764703783 163 Measles(hsa05162) 7753, 61, 131, 3 2.911 0.411114096284 0.742461122144 131 Human cytomegalovirus infection(hsa05163) 7753, 130, 225, 11 2.916 0.0180537459087 0.131238135069 225 Proteasome(hsa03050) 7753, 620, 45, 7 1.945 0.281709467276 0.605579535097 45 Fructose and mannose metabolism(hsa00051) 7753, 1921, 32, 14 1.766 0.0834774357752 0.306731043081 32 Sphingolipid signaling pathway(hsa04071) 7753, 1823, 119, 40 1.43 0.0651378735417 0.267319065444 119 GnRH signaling pathway(hsa04912) 7753, 523, 93, 15 2.391 0.0137597021308 0.119702239801 93 Ovarian steroidogenesis(hsa04913) 7753, 1354, 49, 12 1.402 0.459038967244 0.784839440717 49 Rap1 signaling pathway(hsa04015) 7753, 1977, 206, 72 1.371 0.0182736643767 0.131238135069 206 Ras signaling pathway(hsa04014) 7753, 162, 231, 9 1.865 0.326923991159 0.649735730857 231 Hippo signaling pathway(hsa04390) 7753, 1975, 154, 44 1.122 0.684417669889 0.899259366928 154 Prolactin signaling pathway(hsa04917) 7753, 572, 70, 13 2.517 0.0152012167174 0.120089612067 70 Hematopoietic cell lineage(hsa04640) 7753, 929, 95, 11 0.966 0.939569854862 0.999994743672 95 Estrogen signaling pathway(hsa04915) 7753, 130, 137, 7 3.047 0.0703460396927 0.277866856786 137 Circadian rhythm(hsa04710) 7753, 1961, 31, 8 1.02 0.85042068628 0.996014522543 31 Thyroid hormone synthesis(hsa04918) 7753, 1073, 74, 15 1.465 0.359820063691 0.688383114739 74 Thyroid hormone signaling pathway(hsa04919) 7753, 1250, 116, 33 1.764 0.00664839471267 0.0841457502794 116 AMPK signaling pathway(hsa04152) 7753, 1432, 120, 39 1.76 0.00207149693408 0.0467566450836 120 mTOR signaling pathway(hsa04150) 7753, 357, 153, 12 1.703 0.298049689768 0.619912879728 153 PI3K-Akt signaling pathway(hsa04151) 7753, 1540, 353, 92 1.312 0.0315457622765 0.188084167535 353 Lysine degradation(hsa00310) 7753, 926, 59, 10 1.419 0.525629652168 0.823723403684 59 Tight junction(hsa04530) 7753, 1115, 170, 42 1.718 0.00332566441857 0.0635868474301 170 Acute myeloid leukemia(hsa05221) 7753, 132, 66, 7 6.229 0.00146632476971 0.0405449269662 66 Oxidative phosphorylation(hsa00190) 7753, 370, 120, 9 1.572 0.498441259769 0.807730451729 120 Basal transcription factors(hsa03022) 7753, 1278, 45, 5 0.674 0.986675793767 0.999994743672 45 Phosphatidylinositol signaling system(hsa04070) 7753, 1289, 99, 24 1.458 0.203760617377 0.49913453559 99 Fatty acid metabolism(hsa01212) 7753, 495, 53, 5 1.478 0.649525454633 0.877136938735 53 Glycosphingolipid biosynthesis - ganglio series(hsa00604) 7753, 824, 15, 4 2.509 0.220933517756 0.528901451597 15 Glycosphingolipid biosynthesis - globo and isoglobo series(hsa00603) 7753, 1225, 15, 6 2.532 0.0930091745351 0.330234821945 15 Sphingolipid metabolism(hsa00600) 7753, 1694, 47, 17 1.655 0.10597159458 0.35298773728 47 Glycosphingolipid biosynthesis - lacto and neolacto series(hsa00601) 7753, 66, 26, 2 9.036 0.10552549559 0.35298773728 26 Alanine, aspartate and glutamate metabolism(hsa00250) 7753, 1305, 35, 6 1.018 0.864697706143 0.996014522543 35 Neurotrophin signaling pathway(hsa04722) 7753, 340, 119, 14 2.683 0.00813802202468 0.0918433914214 119 TNF signaling pathway(hsa04668) 7753, 26, 110, 2 5.422 0.290502190372 0.619912879728 110 Necroptosis(hsa04217) 7753, 1813, 162, 47 1.241 0.323187880448 0.646375760895 162 Axon guidance(hsa04360) 7753, 492, 181, 19 1.654 0.155551022874 0.419724664504 181 Glycolysis / Gluconeogenesis(hsa00010) 7753, 1171, 68, 14 1.363 0.492457389436 0.802147087947 68 Neuroactive ligand-receptor interaction(hsa04080) 7753, 19, 337, 1 1.211 0.966579469106 0.999994743672 337 Metabolic pathways(hsa01100) 7753, 1645, 1248, 285 1.076 0.454591924075 0.784839440717 1248 Human immunodeficiency virus 1 infection(hsa05170) 7753, 10, 212, 1 3.657 0.750412231572 0.950204617948 212 Th17 cell differentiation(hsa04659) 7753, 820, 106, 18 1.606 0.19115880372 0.476119968403 106 Th1 and Th2 cell differentiation(hsa04658) 7753, 676, 91, 13 1.638 0.279592597613 0.605145622231 91 Signaling pathways regulating pluripotency of stem cells(hsa04550) 7753, 10, 139, 1 5.578 0.605716344907 0.857611294787 139 Spliceosome(hsa03040) 7753, 875, 133, 19 1.266 0.601846113505 0.857611294787 133 cGMP-PKG signaling pathway(hsa04022) 7753, 1265, 166, 53 1.957 8.82863836423e-06 0.000697462430774 166 Natural killer cell mediated cytotoxicity(hsa04650) 7753, 10, 126, 1 6.153 0.571632416426 0.852055865993 126 Calcium signaling pathway(hsa04020) 7753, 1254, 187, 44 1.455 0.0540978308617 0.239577712494 187 Ubiquitin mediated proteolysis(hsa04120) 7753, 63, 137, 3 2.695 0.455973274499 0.784839440717 137 PPAR signaling pathway(hsa03320) 7753, 1899, 74, 23 1.269 0.461962455612 0.784839440717 74 cAMP signaling pathway(hsa04024) 7753, 11, 212, 3 9.974 0.033772601679 0.190977259291 212 Other glycan degradation(hsa00511) 7753, 1467, 18, 6 1.762 0.318298222222 0.640651198868 18 Fluid shear stress and atherosclerosis(hsa05418) 7753, 987, 139, 35 1.978 0.000686736646778 0.0269096440224 139 Autophagy - animal(hsa04140) 7753, 357, 127, 9 1.539 0.527214723314 0.823723403684 127 Lysosome(hsa04142) 7753, 351, 123, 8 1.437 0.641728073816 0.877136938735 123 Phagosome(hsa04145) 7753, 84, 149, 1 0.619 0.99118245888 0.999994743672 149 Endocytosis(hsa04144) 7753, 1712, 244, 58 1.076 0.801658023836 0.978084693174 244 Nitrogen metabolism(hsa00910) 7753, 436, 17, 1 1.046 0.841512758466 0.996014522543 17 Osteoclast differentiation(hsa04380) 7753, 13, 127, 2 9.392 0.144312279474 0.407674179397 127 Hypertrophic cardiomyopathy (HCM)(hsa05410) 7753, 183, 85, 12 5.981 1.10535590518e-05 0.000698584932075 85 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(hsa05412) 7753, 184, 72, 12 7.023 1.79718295591e-06 0.000189303271356 72 Dilated cardiomyopathy (DCM)(hsa05414) 7753, 183, 90, 15 7.061 4.93418917049e-08 1.55920377787e-05 90 Thiamine metabolism(hsa00730) 7753, 1959, 16, 5 1.237 0.664696312783 0.890017096777 16 Viral myocarditis(hsa05416) 7753, 55, 57, 3 7.419 0.059213492685 0.249486182513 57 Longevity regulating pathway(hsa04211) 7753, 357, 89, 11 2.684 0.0234993745015 0.157995794521 89 Protein processing in endoplasmic reticulum(hsa04141) 7753, 360, 165, 15 1.958 0.0857307491931 0.311389847644 165 Steroid hormone biosynthesis(hsa00140) 7753, 1681, 60, 10 0.769 0.988405784414 0.999994743672 60 Chagas disease (American trypanosomiasis)(hsa05142) 7753, 10, 103, 1 7.527 0.501950193717 0.80926663885 103 African trypanosomiasis(hsa05143) 7753, 1137, 36, 11 2.084 0.0719503948108 0.28069536741 36 Leishmaniasis(hsa05140) 7753, 954, 72, 13 1.467 0.411173089795 0.742461122144 72 Amoebiasis(hsa05146) 7753, 183, 94, 7 3.155 0.0551603952662 0.239577712494 94 Non-homologous end-joining(hsa03450) 7753, 52, 13, 1 11.469 0.249050252859 0.562217079202 13 Malaria(hsa05144) 7753, 1229, 49, 10 1.287 0.632717811684 0.876924686369 49 Toxoplasmosis(hsa05145) 7753, 51, 112, 3 4.072 0.230660109343 0.539915515202 112 Tryptophan metabolism(hsa00380) 7753, 1606, 42, 6 0.69 0.987163982698 0.999994743672 42 Wnt signaling pathway(hsa04310) 7753, 1073, 158, 29 1.326 0.361618977996 0.688383114739 158 Citrate cycle (TCA cycle)(hsa00020) 7753, 5, 30, 1 51.687 0.104375266931 0.35298773728 30 Epithelial cell signaling in Helicobacter pylori infection(hsa05120) 7753, 397, 68, 6 1.723 0.486822385165 0.801228508918 68 Porphyrin and chlorophyll metabolism(hsa00860) 7753, 308, 42, 3 1.798 0.606072173159 0.857611294787 42 Gap junction(hsa04540) 7753, 718, 88, 15 1.841 0.108509831029 0.357178193805 88 ABC transporters(hsa02010) 7753, 394, 45, 2 0.875 0.934374819441 0.999994743672 45 Systemic lupus erythematosus(hsa05322) 7753, 1366, 131, 21 0.91 0.978341689254 0.999994743672 131 Rheumatoid arthritis(hsa05323) 7753, 277, 89, 3 0.943 0.945260037079 0.999994743672 89 Autoimmune thyroid disease(hsa05320) 7753, 739, 51, 2 0.411 0.99741903915 0.999994743672 51 Inflammatory bowel disease (IBD)(hsa05321) 7753, 958, 64, 11 1.391 0.532971285352 0.823723403684 64 Toll-like receptor signaling pathway(hsa04620) 7753, 10, 104, 1 7.455 0.505123271027 0.809627088551 104 NOD-like receptor signaling pathway(hsa04621) 7753, 523, 178, 13 1.083 0.891041506734 0.999994743672 178 RIG-I-like receptor signaling pathway(hsa04622) 7753, 340, 70, 3 0.977 0.927248578787 0.999994743672 70 Cytosolic DNA-sensing pathway(hsa04623) 7753, 423, 63, 4 1.164 0.850103973576 0.996014522543 63 DNA replication(hsa03030) 7753, 1471, 36, 6 0.878 0.933075292354 0.999994743672 36 Autophagy - other(hsa04136) 7753, 357, 32, 3 2.036 0.507297985864 0.809627088551 32 Mitophagy - animal(hsa04137) 7753, 1057, 64, 14 1.605 0.24225478125 0.554728339674 64 SNARE interactions in vesicular transport(hsa04130) 7753, 1934, 34, 12 1.415 0.393074968205 0.725367407691 34 Taurine and hypotaurine metabolism(hsa00430) 7753, 317, 11, 1 2.223 0.602564002403 0.857611294787 11 Nucleotide excision repair(hsa03420) 7753, 1352, 47, 9 1.098 0.818575428404 0.991072166191 47 Glycosaminoglycan biosynthesis - heparan sulfate / heparin(hsa00534) 7753, 203, 24, 1 1.591 0.780948362528 0.967763461016 24 Glycosaminoglycan degradation(hsa00531) 7753, 180, 19, 1 2.267 0.669143036075 0.892190714767 19 Long-term depression(hsa04730) 7753, 1924, 60, 16 1.075 0.822646177246 0.992199206144 60 Glycosaminoglycan biosynthesis - keratan sulfate(hsa00533) 7753, 1204, 14, 5 2.3 0.181532220236 0.465513221732 14 Salivary secretion(hsa04970) 7753, 164, 90, 4 2.101 0.484986423681 0.801228508918 90 Gastric acid secretion(hsa04971) 7753, 164, 75, 6 3.782 0.0410908544232 0.223874310306 75 Pancreatic secretion(hsa04972) 7753, 1976, 97, 29 1.173 0.61335491336 0.857611294787 97 Carbohydrate digestion and absorption(hsa04973) 7753, 523, 44, 7 2.358 0.145782222379 0.407674179397 44 Protein digestion and absorption(hsa04974) 7753, 227, 89, 5 1.919 0.472773646966 0.793387023906 89 Fat digestion and absorption(hsa04975) 7753, 808, 41, 4 0.936 0.913784498763 0.999994743672 41 Bile secretion(hsa04976) 7753, 216, 72, 7 3.49 0.0321887874546 0.188364015475 72 Vitamin digestion and absorption(hsa04977) 7753, 1974, 24, 6 0.982 0.860568868177 0.996014522543 24 Mineral absorption(hsa04978) 7753, 235, 51, 4 2.588 0.300147691767 0.619912879728 51 Cholesterol metabolism(hsa04979) 7753, 1637, 50, 19 1.8 0.0338440712668 0.190977259291 50 Proximal tubule bicarbonate reclamation(hsa04964) 7753, 50, 23, 2 13.483 0.0540289956391 0.239577712494 23 Pentose phosphate pathway(hsa00030) 7753, 1309, 30, 6 1.185 0.745625357997 0.950204617948 30 Phospholipase D signaling pathway(hsa04072) 7753, 155, 147, 9 3.062 0.0291724815465 0.1807549837 147 Staphylococcus aureus infection(hsa05150) 7753, 143, 66, 1 0.821 0.959753144682 0.999994743672 66 Purine metabolism(hsa00230) 7753, 1254, 130, 27 1.284 0.449094458208 0.784839440717 130 Amyotrophic lateral sclerosis (ALS)(hsa05014) 7753, 360, 51, 6 2.534 0.165929758453 0.436422958575 51 Hedgehog signaling pathway(hsa04340) 7753, 992, 47, 6 0.998 0.894206554118 0.999994743672 47 Huntington disease(hsa05016) 7753, 1187, 187, 35 1.222 0.522478079776 0.823723403684 187 Alzheimer disease(hsa05010) 7753, 1877, 165, 55 1.377 0.048340011329 0.233846047102 165 Parkinson disease(hsa05012) 7753, 306, 129, 9 1.768 0.360878400302 0.688383114739 129 Pertussis(hsa05133) 7753, 340, 76, 4 1.2 0.846766413069 0.996014522543 76 Salmonella infection(hsa05132) 7753, 1219, 85, 21 1.571 0.137642125897 0.403410685677 85 Shigellosis(hsa05131) 7753, 1961, 65, 23 1.399 0.236896535665 0.550436068163 65 Glyoxylate and dicarboxylate metabolism(hsa00630) 7753, 5, 30, 1 51.687 0.104375266931 0.35298773728 30 Fc gamma R-mediated phagocytosis(hsa04666) 7753, 738, 90, 13 1.517 0.382795831821 0.71154989915 90 Legionellosis(hsa05134) 7753, 1043, 55, 11 1.487 0.421573830255 0.752640284524 55 Base excision repair(hsa03410) 7753, 672, 33, 4 1.398 0.685827555157 0.899259366928 33 Aminoacyl-tRNA biosynthesis(hsa00970) 7753, 973, 44, 13 2.354 0.0171868956126 0.131238135069 44 Allograft rejection(hsa05330) 7753, 930, 36, 2 0.463 0.992303958552 0.999994743672 36 Graft-versus-host disease(hsa05332) 7753, 888, 38, 2 0.46 0.993057986065 0.999994743672 38 Synaptic vesicle cycle(hsa04721) 7753, 608, 78, 8 1.308 0.705693955798 0.913931516526 78 Long-term potentiation(hsa04720) 7753, 1893, 67, 22 1.345 0.336416932933 0.657623810732 67 Retrograde endocannabinoid signaling(hsa04723) 7753, 524, 141, 13 1.364 0.589168063678 0.857611294787 141 RNA polymerase(hsa03020) 7753, 541, 31, 2 0.925 0.90155016989 0.999994743672 31 Cholinergic synapse(hsa04725) 7753, 1073, 112, 22 1.419 0.298596459379 0.619912879728 112 Glutamatergic synapse(hsa04724) 7753, 956, 114, 16 1.138 0.797580722645 0.978084693174 114 GABAergic synapse(hsa04727) 7753, 119, 89, 3 2.196 0.551756549305 0.834234782682 89 Serotonergic synapse(hsa04726) 7753, 37, 113, 1 1.854 0.865531752577 0.996014522543 113 Dopaminergic synapse(hsa04728) 7753, 1073, 131, 20 1.103 0.827629642745 0.994414323603 131 Amino sugar and nucleotide sugar metabolism(hsa00520) 7753, 1693, 47, 16 1.559 0.191352012618 0.476119968403 47 Vasopressin-regulated water reabsorption(hsa04962) 7753, 1237, 44, 13 1.852 0.100968829301 0.35298773728 44 Endocrine and other factor-regulated calcium reabsorption(hsa04961) 7753, 291, 48, 5 2.775 0.177486549047 0.459719258188 48 Aldosterone-regulated sodium reabsorption(hsa04960) 7753, 1977, 37, 18 1.908 0.0151493785843 0.120089612067 37 Collecting duct acid secretion(hsa04966) 7753, 844, 27, 4 1.361 0.681619667054 0.899259366928 27 One carbon pool by folate(hsa00670) 7753, 1984, 20, 7 1.368 0.533612659035 0.823723403684 20 Pantothenate and CoA biosynthesis(hsa00770) 7753, 126, 19, 2 6.477 0.153338163557 0.419724664504 19 Notch signaling pathway(hsa04330) 7753, 41, 48, 1 3.94 0.610874375685 0.857611294787 48 Pentose and glucuronate interconversions(hsa00040) 7753, 91, 33, 1 2.582 0.690041611654 0.901046071416 33 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate(hsa00532) 7753, 1130, 20, 6 2.058 0.217685308691 0.525103492719 20 Biosynthesis of amino acids(hsa01230) 7753, 1447, 75, 17 1.214 0.648127723218 0.877136938735 75 Glutathione metabolism(hsa00480) 7753, 69, 56, 1 2.006 0.800473340119 0.978084693174 56 Primary bile acid biosynthesis(hsa00120) 7753, 1839, 17, 7 1.736 0.266591611175 0.585020480079 17 JAK-STAT signaling pathway(hsa04630) 7753, 10, 162, 2 9.572 0.135529312045 0.403410685677 162 Tyrosine metabolism(hsa00350) 7753, 1720, 36, 7 0.876 0.93792481658 0.999994743672 36 TGF-beta signaling pathway(hsa04350) 7753, 1844, 89, 32 1.512 0.0524939320065 0.239577712494 89 Bacterial invasion of epithelial cells(hsa05100) 7753, 1938, 74, 32 1.73 0.00492597996144 0.0707549849006 74 Metabolism of xenobiotics by cytochrome P450(hsa00980) 7753, 740, 74, 4 0.566 0.9969026802 0.999994743672 74 Thyroid cancer(hsa05216) 7753, 492, 37, 6 2.555 0.143450760023 0.407674179397 37 Cell cycle(hsa04110) 7753, 1610, 124, 31 1.204 0.555188624496 0.835426692099 124 Drug metabolism - other enzymes(hsa00983) 7753, 818, 79, 9 1.08 0.866784790188 0.996014522543 79 Oocyte meiosis(hsa04114) 7753, 1977, 125, 44 1.38 0.0799796325305 0.300875760472 125 p53 signaling pathway(hsa04115) 7753, 353, 72, 8 2.44 0.110267852555 0.359223107292 72 Mucin type O-glycan biosynthesis(hsa00512) 7753, 827, 31, 4 1.21 0.772781285564 0.961412937946 31 Gastric cancer(hsa05226) 7753, 196, 149, 10 2.655 0.0443435247804 0.229713997223 149 Hepatocellular carcinoma(hsa05225) 7753, 128, 168, 10 3.605 0.0060730943799 0.0834390358282 168 mRNA surveillance pathway(hsa03015) 7753, 1257, 91, 26 1.762 0.0203725038115 0.143060248987 91 Non-small cell lung cancer(hsa05223) 7753, 572, 66, 15 3.08 0.000856765587888 0.0270737925773 66 RNA transport(hsa03013) 7753, 1038, 160, 30 1.4 0.226752937244 0.534763667424 160 Ribosome(hsa03010) 7753, 1933, 134, 41 1.227 0.394820234566 0.725367407691 134 Chronic myeloid leukemia(hsa05220) 7753, 542, 76, 14 2.635 0.00751653745169 0.0879713272124 76 Primary immunodeficiency(hsa05340) 7753, 1240, 36, 5 0.868 0.933361152515 0.999994743672 36 Propanoate metabolism(hsa00640) 7753, 540, 32, 2 0.897 0.910927020127 0.999994743672 32 Hippo signaling pathway - multiple species(hsa04392) 7753, 1920, 29, 8 1.114 0.770204860686 0.961412937946 29 RNA degradation(hsa03018) 7753, 372, 79, 8 2.111 0.20740589869 0.504155876816 79 Regulation of actin cytoskeleton(hsa04810) 7753, 1977, 214, 76 1.393 0.00873919302121 0.0927592071911 214 Nicotinate and nicotinamide metabolism(hsa00760) 7753, 153, 30, 1 1.689 0.78711551672 0.971595715952 30 Insulin secretion(hsa04911) 7753, 451, 86, 11 2.199 0.0792139296967 0.300875760472 86 Selenocompound metabolism(hsa00450) 7753, 1980, 17, 6 1.382 0.539146661026 0.823723403684 17 Arginine and proline metabolism(hsa00330) 7753, 1588, 49, 10 0.996 0.892764672031 0.999994743672 49 Maturity onset diabetes of the young(hsa04950) 7753, 161, 26, 2 3.704 0.337136257401 0.657623810732 26 alpha-Linolenic acid metabolism(hsa00592) 7753, 478, 24, 1 0.676 0.941084348607 0.999994743672 24 Arachidonic acid metabolism(hsa00590) 7753, 585, 62, 2 0.428 0.997666878702 0.999994743672 62 Linoleic acid metabolism(hsa00591) 7753, 585, 28, 2 0.947 0.890261131408 0.999994743672 28 Asthma(hsa05310) 7753, 690, 29, 1 0.387 0.987290670909 0.999994743672 29 Cell adhesion molecules (CAMs)(hsa04514) 7753, 81, 143, 5 3.347 0.125522790598 0.385099046882 143 Morphine addiction(hsa05032) 7753, 117, 91, 4 2.913 0.27042538034 0.589340828878 91 Nicotine addiction(hsa05033) 7753, 524, 40, 2 0.74 0.95718081837 0.999994743672 40 Cocaine addiction(hsa05030) 7753, 340, 49, 3 1.396 0.765262875343 0.961412937946 49 Amphetamine addiction(hsa05031) 7753, 381, 68, 4 1.197 0.840262401848 0.996014522543 68 Ascorbate and aldarate metabolism(hsa00053) 7753, 817, 27, 2 0.703 0.94845025525 0.999994743672 27 Galactose metabolism(hsa00052) 7753, 1688, 31, 12 1.778 0.125341842264 0.385099046882 31 Alcoholism(hsa05034) 7753, 1941, 180, 49 1.087 0.772196645224 0.961412937946 180 Mismatch repair(hsa03430) 7753, 1352, 23, 7 1.745 0.304658282903 0.625142970114 23 Vascular smooth muscle contraction(hsa04270) 7753, 21, 132, 3 8.391 0.0488412630024 0.233846047102 132 Peroxisome(hsa04146) 7753, 461, 83, 6 1.216 0.812617193883 0.987642435642 83 Taste transduction(hsa04742) 7753, 117, 82, 3 2.424 0.484924297923 0.801228508918 82 Renin-angiotensin system(hsa04614) 7753, 1042, 23, 3 0.97 0.86343121845 0.996014522543 23 Melanoma(hsa05218) 7753, 102, 72, 6 6.334 0.00402448401456 0.0635868474301 72 Bladder cancer(hsa05219) 7753, 1037, 41, 10 1.824 0.196574189044 0.485292529202 41 Platelet activation(hsa04611) 7753, 1073, 124, 29 1.69 0.0278938837159 0.179753893662 124 Complement and coagulation cascades(hsa04610) 7753, 1177, 79, 14 1.167 0.750642042039 0.950204617948 79 Small cell lung cancer(hsa05222) 7753, 708, 93, 19 2.237 0.0071997943137 0.087505192428 93 Antigen processing and presentation(hsa04612) 7753, 935, 72, 12 1.382 0.527573036347 0.823723403684 72 Pancreatic cancer(hsa05212) 7753, 542, 75, 14 2.67 0.00665710049679 0.0841457502794 75 Endometrial cancer(hsa05213) 7753, 128, 58, 6 6.266 0.00393721893295 0.0635868474301 58 Colorectal cancer(hsa05210) 7753, 502, 86, 13 2.335 0.0309380325799 0.188008044139 86 Renal cell carcinoma(hsa05211) 7753, 492, 69, 12 2.741 0.0118844458607 0.110455437999 69 Folate biosynthesis(hsa00790) 7753, 1921, 26, 8 1.242 0.64421891937 0.877136938735 26 Basal cell carcinoma(hsa05217) 7753, 101, 63, 2 2.437 0.593422046607 0.857611294787 63 Glioma(hsa05214) 7753, 605, 75, 13 2.221 0.0406638810361 0.223874310306 75 Prostate cancer(hsa05215) 7753, 128, 97, 6 3.747 0.0455495607866 0.230337009269 97 Drug metabolism - cytochrome P450(hsa00982) 7753, 740, 70, 5 0.748 0.982430376245 0.999994743672 70 Phototransduction(hsa04744) 7753, 1900, 28, 8 1.166 0.721032905728 0.929985298816 28 Pathogenic Escherichia coli infection(hsa05130) 7753, 1664, 55, 21 1.779 0.0274109745221 0.179753893662 55 Starch and sucrose metabolism(hsa00500) 7753, 1604, 36, 13 1.745 0.128683068048 0.390998552914 36 Focal adhesion(hsa04510) 7753, 155, 199, 15 3.77 0.000187991169153 0.00990086824204 199 Olfactory transduction(hsa04740) 7753, 76, 444, 1 0.23 0.999994743672 0.999994743672 444 HIF-1 signaling pathway(hsa04066) 7753, 11, 100, 2 14.096 0.0683900877183 0.277067534859 100 Type I diabetes mellitus(hsa04940) 7753, 1022, 42, 5 0.903 0.928545918483 0.999994743672 42 NF-kappa B signaling pathway(hsa04064) 7753, 1137, 94, 12 0.87 0.976441876858 0.999994743672 94 Chemokine signaling pathway(hsa04062) 7753, 128, 190, 6 1.913 0.459564282825 0.784839440717 190 Butanoate metabolism(hsa00650) 7753, 44, 28, 1 6.293 0.436397344759 0.770399781809 28 Cytokine-cytokine receptor interaction(hsa04060) 7753, 3, 294, 1 8.79 0.537762528186 0.823723403684 294 Histidine metabolism(hsa00340) 7753, 185, 23, 1 1.822 0.742816470305 0.950204617948 23 Pyrimidine metabolism(hsa00240) 7753, 1144, 57, 9 1.07 0.852640395564 0.996014522543 57 Other types of O-glycan biosynthesis(hsa00514) 7753, 1896, 22, 7 1.301 0.597209198336 0.857611294787 22 EGFR tyrosine kinase inhibitor resistance(hsa01521) 7753, 128, 79, 6 4.6 0.0181875888089 0.131238135069 79 Fatty acid elongation(hsa00062) 7753, 515, 30, 4 2.007 0.419137056116 0.752541532572 30 Terpenoid backbone biosynthesis(hsa00900) 7753, 182, 22, 2 3.873 0.307744860233 0.626417873853 22 Fatty acid biosynthesis(hsa00061) 7753, 1464, 13, 3 1.222 0.704206918364 0.913931516526 13 Valine, leucine and isoleucine degradation(hsa00280) 7753, 167, 48, 3 2.902 0.343481176803 0.665889888772 48 Cellular senescence(hsa04218) 7753, 1099, 158, 35 1.563 0.042707741777 0.227356298624 158 Insulin signaling pathway(hsa04910) 7753, 161, 137, 11 3.866 0.00183531090035 0.0446121726546 137 Prion diseases(hsa05020) 7753, 1323, 35, 8 1.339 0.595057749298 0.857611294787 35 Glycine, serine and threonine metabolism(hsa00260) 7753, 1375, 40, 9 1.269 0.648646442298 0.877136938735 40 Apoptosis(hsa04210) 7753, 10, 136, 1 5.701 0.598281918639 0.857611294787 136 Longevity regulating pathway - multiple species(hsa04213) 7753, 357, 62, 7 2.452 0.140955893631 0.407674179397 62 Apoptosis - multiple species(hsa04215) 7753, 306, 33, 1 0.768 0.939761549753 0.999994743672 33 2-Oxocarboxylic acid metabolism(hsa01210) 7753, 126, 18, 1 3.418 0.546797412888 0.830711454195 18 Ferroptosis(hsa04216) 7753, 1759, 40, 16 1.763 0.0696590841907 0.277866856786 40 Mannose type O-glycan biosynthesis(hsa00515) 7753, 1869, 22, 4 0.754 0.944246421037 0.999994743672 22 VEGF signaling pathway(hsa04370) 7753, 10, 59, 2 26.281 0.0212411433418 0.145917419479 59 Apelin signaling pathway(hsa04371) 7753, 130, 137, 6 2.612 0.190779264704 0.476119968403 137 Proteoglycans in cancer(hsa05205) 7753, 131, 201, 8 2.356 0.156732627884 0.419724664504 201 Chemical carcinogenesis(hsa05204) 7753, 740, 82, 4 0.511 0.998827836127 0.999994743672 82 MicroRNAs in cancer(hsa05206) 7753, 1975, 299, 89 1.168 0.331142665589 0.654006764539 299 Pathways in cancer(hsa05200) 7753, 150, 530, 22 2.145 0.00909979564217 0.0927592071911 530 Viral carcinogenesis(hsa05203) 7753, 392, 201, 16 1.574 0.298422809011 0.619912879728 201 Transcriptional misregulation in cancer(hsa05202) 7753, 132, 185, 6 1.905 0.467152400192 0.789412612088 185 T cell receptor signaling pathway(hsa04660) 7753, 353, 101, 9 1.957 0.241983603431 0.554728339674 101 Ubiquinone and other terpenoid-quinone biosynthesis(hsa00130) 7753, 386, 11, 3 5.478 0.0611317042279 0.254179191264 11 B cell receptor signaling pathway(hsa04662) 7753, 14, 70, 2 15.822 0.0524087478814 0.239577712494 70 Arginine biosynthesis(hsa00220) 7753, 1992, 21, 7 1.297 0.598118579786 0.857611294787 21 Fc epsilon RI signaling pathway(hsa04664) 7753, 10, 67, 1 11.572 0.364128090959 0.689008842773 67 Central carbon metabolism in cancer(hsa05230) 7753, 1158, 65, 21 2.163 0.00359417008989 0.0635868474301 65 Vibrio cholerae infection(hsa05110) 7753, 934, 50, 9 1.494 0.474525783286 0.793387023906 50 Cushing syndrome(hsa04934) 7753, 1081, 155, 28 1.296 0.42941747689 0.762336644366 155 Fanconi anemia pathway(hsa03460) 7753, 41, 54, 1 3.502 0.65268221288 0.87764927349 54 Type II diabetes mellitus(hsa04930) 7753, 1989, 46, 18 1.525 0.167111322746 0.436422958575 46 Insulin resistance(hsa04931) 7753, 907, 108, 24 1.9 0.014662713289 0.120089612067 108 C-type lectin receptor signaling pathway(hsa04625) 7753, 1893, 104, 31 1.221 0.490871628004 0.802147087947 104 Biosynthesis of unsaturated fatty acids(hsa01040) 7753, 515, 27, 6 3.345 0.0466505335228 0.230337009269 27 Steroid biosynthesis(hsa00100) 7753, 342, 19, 4 4.773 0.0462127197122 0.230337009269 19 Homologous recombination(hsa03440) 7753, 984, 41, 8 1.537 0.457506250225 0.784839440717 41 Pyruvate metabolism(hsa00620) 7753, 5, 39, 1 39.759 0.137640012267 0.403410685677 39 beta-Alanine metabolism(hsa00410) 7753, 1106, 31, 6 1.357 0.631097298373 0.876924686369 31 Fatty acid degradation(hsa00071) 7753, 167, 44, 1 1.055 0.91197016118 0.999994743672 44 N-Glycan biosynthesis(hsa00510) 7753, 1743, 49, 21 1.906 0.0103744607941 0.102447800342 49 Tuberculosis(hsa05152) 7753, 517, 177, 15 1.271 0.680513502964 0.899259366928 177 Melanogenesis(hsa04916) 7753, 130, 101, 5 2.952 0.182669745237 0.465513221732 101 Carbon metabolism(hsa01200) 7753, 5, 116, 1 13.367 0.369372364688 0.694771828819 116 Breast cancer(hsa05224) 7753, 128, 147, 6 2.472 0.226766871629 0.534763667424 147 Choline metabolism in cancer(hsa05231) 7753, 793, 99, 18 1.778 0.0824043161331 0.306350163507 99 Adherens junction(hsa04520) 7753, 1988, 72, 34 1.842 0.000766413912032 0.0269096440224 72 FoxO signaling pathway(hsa04068) 7753, 201, 131, 7 2.061 0.309244266839 0.626417873853 131 Non-alcoholic fatty liver disease (NAFLD)(hsa04932) 7753, 1867, 145, 44 1.26 0.292406961298 0.619912879728 145 Inflammatory mediator regulation of TRP channels(hsa04750) 7753, 1104, 100, 22 1.545 0.154819964746 0.419724664504 100 Cysteine and methionine metabolism(hsa00270) 7753, 169, 47, 4 3.904 0.115986703199 0.370220183947 47 Cardiac muscle contraction(hsa04260) 7753, 181, 74, 8 4.631 0.00366629313439 0.0635868474301 74 Adrenergic signaling in cardiomyocytes(hsa04261) 7753, 1292, 145, 51 2.111 9.35430535847e-07 0.000147798024664 145 IL-17 signaling pathway(hsa04657) 7753, 544, 93, 9 1.379 0.635856890639 0.877136938735 93 ErbB signaling pathway(hsa04012) 7753, 502, 85, 11 1.999 0.137874538143 0.403410685677 85