# Analysis title: 72934_peaks analysis from Cistrome-GO # Mode: Solo mode # Specie: hg38 # Peak bed file name: 72934_peaks.bed # Top peaks to use: 10000 # Half-decay distance: 10000bp # FDR cutoff of GO/KEGG terms to return: 0.2 # Minimum and maximum gene number in GO and KEGG gene sets: 10, 2000 # Term N,n,B,b Erichment p_value FDR Gene_number ion antiporter activity(GO:0099516) 17006, 360, 62, 3 2.286 0.420803031683 0.814304198748 62 lipoprotein particle receptor activity(GO:0030228) 17006, 1681, 16, 1 0.632 0.819093996588 0.954716720116 16 extracellular matrix binding(GO:0050840) 17006, 1461, 56, 8 1.663 0.336713733431 0.756314832265 56 nucleoside-triphosphatase regulator activity(GO:0060589) 17006, 268, 353, 15 2.696 0.00694152649569 0.16614791553 353 glutamate receptor activity(GO:0008066) 17006, 1320, 27, 2 0.954 0.805485758702 0.950779632485 27 peptide N-acetyltransferase activity(GO:0034212) 17006, 50, 74, 1 4.596 0.524169316532 0.844743089721 74 intramolecular transferase activity, phosphotransferases(GO:0016868) 17006, 0, 11, 0 0.0 1.0 1.0 11 poly-pyrimidine tract binding(GO:0008187) 17006, 1604, 32, 5 1.657 0.41766460242 0.814304198748 32 intramolecular transferase activity(GO:0016866) 17006, 1871, 26, 1 0.35 0.952808401421 1.0 26 ion channel binding(GO:0044325) 17006, 360, 124, 8 3.048 0.0364079879158 0.343720048811 124 molecular function regulator(GO:0098772) 17006, 47, 1872, 13 2.513 0.0206416296365 0.269908903981 1872 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) 17006, 730, 14, 1 1.664 0.595418049093 0.881268858068 14 intramolecular oxidoreductase activity(GO:0016860) 17006, 730, 49, 3 1.426 0.668862668663 0.900688262904 49 hexose transmembrane transporter activity(GO:0015149) 17006, 1491, 21, 3 1.629 0.488453010879 0.836769419963 21 prenyltransferase activity(GO:0004659) 17006, 363, 16, 2 5.856 0.127952607298 0.568921958917 16 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) 17006, 736, 60, 5 1.925 0.367537595711 0.787689494542 60 diacylglycerol binding(GO:0019992) 17006, 26, 12, 2 109.013 0.000719175521659 0.0464317696171 12 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) 17006, 1589, 19, 1 0.563 0.859024346307 0.977282103233 19 polynucleotide adenylyltransferase activity(GO:0004652) 17006, 1511, 13, 3 2.597 0.217588436861 0.683188009961 13 transmembrane receptor protein tyrosine kinase activity(GO:0004714) 17006, 1110, 64, 7 1.676 0.385241385334 0.802327320665 64 non-membrane spanning protein tyrosine kinase activity(GO:0004715) 17006, 1734, 46, 10 2.132 0.078323277928 0.47023778186 46 protein serine/threonine/tyrosine kinase activity(GO:0004712) 17006, 131, 43, 4 12.076 0.00241690519676 0.0832221022749 43 protein tyrosine kinase activity(GO:0004713) 17006, 1249, 178, 22 1.683 0.0867445597862 0.485742494715 178 water transmembrane transporter activity(GO:0005372) 17006, 856, 13, 4 6.113 0.0134383404943 0.228232607772 13 cytokine receptor activity(GO:0004896) 17006, 1944, 95, 14 1.289 0.543601217268 0.853404342611 95 neurotransmitter receptor activity(GO:0030594) 17006, 232, 116, 2 1.264 0.840809421896 0.966135854081 116 aldehyde dehydrogenase (NAD) activity(GO:0004029) 17006, 1711, 14, 1 0.71 0.779847091527 0.942201222863 14 cAMP response element binding(GO:0035497) 17006, 1862, 14, 5 3.262 0.0474169266019 0.371073372574 14 serine hydrolase activity(GO:0017171) 17006, 284, 213, 1 0.281 0.999390647088 1.0 213 omega peptidase activity(GO:0008242) 17006, 0, 15, 0 0.0 1.0 1.0 15 transferase activity, transferring pentosyl groups(GO:0016763) 17006, 1664, 53, 7 1.35 0.575335503042 0.872718905496 53 regulatory region nucleic acid binding(GO:0001067) 17006, 1997, 933, 130 1.187 0.176376571736 0.623962323985 933 histone kinase activity(GO:0035173) 17006, 118, 17, 1 8.478 0.257650845594 0.711021691352 17 SMAD binding(GO:0046332) 17006, 923, 80, 15 3.455 0.000266460666007 0.0263580666848 80 proximal promoter sequence-specific DNA binding(GO:0000987) 17006, 1484, 537, 60 1.28 0.200893502707 0.660901236613 537 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) 17006, 1478, 20, 5 2.877 0.0896276573851 0.487291421467 20 channel inhibitor activity(GO:0016248) 17006, 1321, 39, 5 1.65 0.441895397195 0.821849554378 39 protein serine/threonine kinase inhibitor activity(GO:0030291) 17006, 1261, 33, 6 2.452 0.126121080445 0.566602479291 33 peptidoglycan muralytic activity(GO:0061783) 17006, 0, 13, 0 0.0 1.0 1.0 13 protein tyrosine kinase activator activity(GO:0030296) 17006, 0, 19, 0 0.0 1.0 1.0 19 G-rich strand telomeric DNA binding(GO:0098505) 17006, 1209, 11, 1 1.279 0.601139440673 0.883159820389 11 purinergic nucleotide receptor activity(GO:0001614) 17006, 1338, 22, 5 2.889 0.0913303841353 0.489576697981 22 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides(GO:0016818) 17006, 1809, 910, 110 1.136 0.461176135288 0.821849554378 910 protein N-terminus binding(GO:0047485) 17006, 296, 107, 3 1.611 0.677651624804 0.903244036674 107 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) 17006, 309, 11, 1 5.003 0.308488247417 0.735062494398 11 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) 17006, 567, 148, 8 1.621 0.449858744023 0.821849554378 148 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) 17006, 806, 92, 7 1.605 0.46070414437 0.821849554378 92 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) 17006, 383, 34, 2 2.612 0.420437877663 0.814304198748 34 carbohydrate transmembrane transporter activity(GO:0015144) 17006, 568, 38, 3 2.364 0.358774251879 0.780325126639 38 phospholipase C activity(GO:0004629) 17006, 1902, 29, 6 1.85 0.272573277695 0.720123263067 29 misfolded protein binding(GO:0051787) 17006, 664, 23, 2 2.227 0.441107799504 0.821849554378 23 fibronectin binding(GO:0001968) 17006, 1942, 26, 5 1.684 0.382320303024 0.7994673543 26 endonuclease activity(GO:0004519) 17006, 1761, 122, 15 1.187 0.682222326366 0.904028572842 122 acyl-CoA dehydrogenase activity(GO:0003995) 17006, 325, 12, 2 8.721 0.0640188978948 0.437957096194 12 phospholipase A2 activity(GO:0004623) 17006, 1013, 35, 5 2.398 0.189983721178 0.637280604303 35 phospholipase activity(GO:0004620) 17006, 1316, 105, 12 1.477 0.402657867657 0.81055633192 105 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) 17006, 1244, 99, 14 1.933 0.0824114710607 0.478264323627 99 heat shock protein binding(GO:0031072) 17006, 664, 119, 7 1.507 0.548070533371 0.856515674693 119 neuropeptide receptor activity(GO:0008188) 17006, 1685, 50, 3 0.606 0.964904954058 1.0 50 RAGE receptor binding(GO:0050786) 17006, 1995, 11, 4 3.1 0.0893639293716 0.487291421467 11 dopamine receptor binding(GO:0050780) 17006, 1447, 16, 1 0.735 0.785388493887 0.944477664942 16 pyridoxal phosphate binding(GO:0030170) 17006, 669, 53, 3 1.439 0.667905065952 0.900688262904 53 phosphatidylinositol 3-kinase activity(GO:0035004) 17006, 13, 82, 1 15.953 0.256242543278 0.711021691352 82 SNAP receptor activity(GO:0005484) 17006, 441, 32, 1 1.205 0.782540066342 0.943248411355 32 immunoglobulin binding(GO:0019865) 17006, 1461, 23, 2 1.012 0.755825100123 0.930059447969 23 protein transporter activity(GO:0008565) 17006, 1592, 96, 9 1.001 0.872170344017 0.983180024081 96 small ribosomal subunit rRNA binding(GO:0070181) 17006, 0, 11, 0 0.0 1.0 1.0 11 DNA polymerase binding(GO:0070182) 17006, 141, 18, 1 6.701 0.305977752941 0.735062494398 18 intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) 17006, 154, 18, 1 6.135 0.32566170721 0.745916947999 18 cation:cation antiporter activity(GO:0015491) 17006, 360, 27, 1 1.75 0.669269414791 0.900688262904 27 RNA polymerase II general transcription initiation factor binding(GO:0001091) 17006, 52, 20, 1 16.352 0.171249598964 0.623962323985 20 C4-dicarboxylate transmembrane transporter activity(GO:0015556) 17006, 841, 14, 2 2.889 0.292305105106 0.735062494398 14 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) 17006, 1027, 18, 1 0.92 0.772196989894 0.939763382117 18 basal transcription machinery binding(GO:0001098) 17006, 76, 55, 2 8.137 0.119405199073 0.558124754036 55 C2H2 zinc finger domain binding(GO:0070742) 17006, 1163, 15, 2 1.95 0.449452612106 0.821849554378 15 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028) 17006, 202, 42, 1 2.004 0.688462139171 0.909439117345 42 ceramide binding(GO:0097001) 17006, 947, 14, 3 3.848 0.110282330606 0.534843415567 14 single-stranded DNA-dependent ATPase activity(GO:0043142) 17006, 1540, 14, 1 0.789 0.75216464692 0.930059447969 14 ribonucleoprotein complex binding(GO:0043021) 17006, 580, 129, 7 1.591 0.50026558198 0.844743089721 129 syntaxin-1 binding(GO:0017075) 17006, 0, 22, 0 0.0 1.0 1.0 22 ribosome binding(GO:0043022) 17006, 785, 57, 2 0.76 0.924206883371 1.0 57 histone deacetylase binding(GO:0042826) 17006, 141, 112, 6 6.461 0.00347728821846 0.0970821278289 112 motor activity(GO:0003774) 17006, 183, 138, 4 2.694 0.287187912303 0.735062494398 138 microtubule motor activity(GO:0003777) 17006, 410, 84, 4 1.975 0.449488249564 0.821849554378 84 U6 snRNA binding(GO:0017070) 17006, 785, 11, 1 1.969 0.522636438238 0.844743089721 11 benzodiazepine receptor activity(GO:0008503) 17006, 626, 11, 1 2.47 0.467947011235 0.822090582663 11 nucleotide-sugar transmembrane transporter activity(GO:0005338) 17006, 1507, 14, 1 0.806 0.746822420767 0.928360482133 14 transferase activity, transferring sulfur-containing groups(GO:0016782) 17006, 1934, 69, 3 0.382 0.997527525587 1.0 69 sulfurtransferase activity(GO:0016783) 17006, 1934, 11, 1 0.799 0.735372168893 0.921739698866 11 phosphotransferase activity, for other substituted phosphate groups(GO:0016780) 17006, 1787, 19, 3 1.503 0.519863066243 0.844743089721 19 type I interferon receptor binding(GO:0005132) 17006, 0, 16, 0 0.0 1.0 1.0 16 ligand-gated channel activity(GO:0022834) 17006, 95, 139, 3 3.864 0.224343961917 0.688808413229 139 cyclic nucleotide binding(GO:0030551) 17006, 24, 37, 2 38.302 0.0074047479683 0.169441732366 37 hydrolase activity, acting on ester bonds(GO:0016788) 17006, 1902, 746, 90 1.079 0.754920867301 0.930059447969 746 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) 17006, 1460, 24, 1 0.485 0.90760673134 1.0 24 beta-catenin binding(GO:0008013) 17006, 1867, 83, 14 1.536 0.274081599071 0.720423134454 83 cargo receptor activity(GO:0038024) 17006, 1889, 86, 5 0.523 0.996020782631 1.0 86 thiol-dependent ubiquitin-specific protease activity(GO:0004843) 17006, 185, 104, 2 1.768 0.703685633933 0.91426919723 104 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) 17006, 182, 26, 1 3.594 0.475491861325 0.826262147787 26 Rac guanyl-nucleotide exchange factor activity(GO:0030676) 17006, 174, 17, 1 5.749 0.326879505882 0.746326873734 17 nucleotidyltransferase activity(GO:0016779) 17006, 1339, 130, 8 0.782 0.977081586349 1.0 130 4 iron, 4 sulfur cluster binding(GO:0051539) 17006, 115, 42, 2 7.042 0.13549266474 0.578363316844 42 phosphotransferase activity, alcohol group as acceptor(GO:0016773) 17006, 158, 792, 17 2.31 0.0160744241776 0.236572150819 792 transferase activity, transferring phosphorus-containing groups(GO:0016772) 17006, 158, 1005, 17 1.821 0.122166459824 0.56591010313 1005 iron-sulfur cluster binding(GO:0051536) 17006, 206, 63, 3 3.931 0.179580391168 0.627201030964 63 2 iron, 2 sulfur cluster binding(GO:0051537) 17006, 206, 21, 1 3.931 0.438813048544 0.821849554378 21 exoribonuclease activity(GO:0004532) 17006, 432, 39, 2 2.019 0.543156343568 0.853404342611 39 phosphotransferase activity, phosphate group as acceptor(GO:0016776) 17006, 1858, 38, 5 1.204 0.680188667776 0.903773478035 38 fucosyltransferase activity(GO:0008417) 17006, 0, 13, 0 0.0 1.0 1.0 13 co-receptor binding(GO:0039706) 17006, 0, 13, 0 0.0 1.0 1.0 13 adenylyltransferase activity(GO:0070566) 17006, 1511, 29, 3 1.164 0.712746574942 0.918461791404 29 vitamin transmembrane transporter activity(GO:0090482) 17006, 163, 26, 2 8.025 0.0978271983265 0.502763661051 26 monovalent inorganic cation transmembrane transporter activity(GO:0015077) 17006, 124, 380, 6 2.165 0.335312843336 0.756314832265 380 proteoglycan binding(GO:0043394) 17006, 1249, 35, 2 0.778 0.882472530344 0.984442898321 35 L-amino acid transmembrane transporter activity(GO:0015179) 17006, 1662, 54, 8 1.516 0.425417017564 0.817536696504 54 retinoic acid binding(GO:0001972) 17006, 1438, 26, 2 0.91 0.808840838216 0.950779632485 26 basic amino acid transmembrane transporter activity(GO:0015174) 17006, 0, 12, 0 0.0 1.0 1.0 12 neutral amino acid transmembrane transporter activity(GO:0015175) 17006, 1419, 31, 2 0.773 0.876542830654 0.983180024081 31 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) 17006, 484, 34, 5 5.167 0.0152449660564 0.228232607772 34 potassium ion transmembrane transporter activity(GO:0015079) 17006, 123, 160, 4 3.457 0.174912013872 0.623962323985 160 bile acid transmembrane transporter activity(GO:0015125) 17006, 0, 16, 0 0.0 1.0 1.0 16 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 17006, 13, 17, 2 153.9 0.000428704629288 0.0340655293888 17 intracellular calcium activated chloride channel activity(GO:0005229) 17006, 1397, 18, 3 2.029 0.358984879585 0.780325126639 18 protein C-terminus binding(GO:0008022) 17006, 267, 186, 7 2.397 0.171847349836 0.623962323985 186 organic acid transmembrane transporter activity(GO:0005342) 17006, 1676, 156, 19 1.236 0.592247559024 0.880207012751 156 cyclic nucleotide-gated ion channel activity(GO:0043855) 17006, 95, 11, 1 16.274 0.138946553613 0.582865053113 11 activating transcription factor binding(GO:0033613) 17006, 8, 73, 1 29.12 0.162758789224 0.622703071364 73 receptor serine/threonine kinase binding(GO:0033612) 17006, 5, 23, 1 147.878 0.0314471844819 0.320680675622 23 monocarboxylic acid transmembrane transporter activity(GO:0008028) 17006, 237, 53, 1 1.354 0.807511965056 0.950779632485 53 volume-sensitive anion channel activity(GO:0005225) 17006, 119, 11, 1 12.992 0.163792447841 0.623962323985 11 sulfotransferase activity(GO:0008146) 17006, 1715, 52, 2 0.381 0.990505325365 1.0 52 calcium activated cation channel activity(GO:0005227) 17006, 834, 28, 2 1.456 0.647400587634 0.898965850169 28 organophosphate ester transmembrane transporter activity(GO:0015605) 17006, 848, 27, 4 2.971 0.146989259548 0.598429452064 27 nucleosome binding(GO:0031491) 17006, 58, 70, 1 4.189 0.544482918971 0.853491434442 70 chromatin DNA binding(GO:0031490) 17006, 92, 108, 2 3.423 0.413454007909 0.814304198748 108 structural constituent of cytoskeleton(GO:0005200) 17006, 102, 98, 2 3.403 0.408033113534 0.812324557007 98 heparan sulfate sulfotransferase activity(GO:0034483) 17006, 1715, 15, 1 0.661 0.803420406591 0.950779632485 15 phosphatidylinositol 3-kinase binding(GO:0043548) 17006, 319, 31, 3 5.159 0.085198806703 0.483573446836 31 phosphatidate phosphatase activity(GO:0008195) 17006, 984, 13, 1 1.329 0.63041634794 0.891943663175 13 protein kinase C activity(GO:0004697) 17006, 1245, 16, 1 0.854 0.7562922907 0.930059447969 16 transforming growth factor beta binding(GO:0050431) 17006, 1699, 22, 6 2.73 0.0697576349731 0.458455131176 22 sulfur compound binding(GO:1901681) 17006, 129, 236, 2 1.117 0.91660540179 1.0 236 sequence-specific DNA binding(GO:0043565) 17006, 1448, 1114, 115 1.212 0.154249500881 0.60816692523 1114 proton-exporting ATPase activity, phosphorylative mechanism(GO:0008553) 17006, 452, 14, 1 2.687 0.467565576536 0.822090582663 14 insulin receptor substrate binding(GO:0043560) 17006, 1245, 11, 4 4.967 0.022947661511 0.282201599296 11 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764) 17006, 1352, 27, 4 1.863 0.374376804106 0.792482046396 27 magnesium ion binding(GO:0000287) 17006, 126, 212, 3 1.91 0.636362516709 0.891943663175 212 S-acyltransferase activity(GO:0016417) 17006, 917, 32, 3 1.739 0.503425011557 0.844743089721 32 14-3-3 protein binding(GO:0071889) 17006, 1047, 28, 4 2.32 0.256204341149 0.711021691352 28 calcium ion binding(GO:0005509) 17006, 128, 696, 9 1.718 0.432261024312 0.821849554378 696 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) 17006, 468, 12, 4 12.113 0.00104674920602 0.0491496331736 12 acylglycerol O-acyltransferase activity(GO:0016411) 17006, 1598, 28, 6 2.28 0.148487620752 0.598429452064 28 fatty acid binding(GO:0005504) 17006, 1576, 35, 3 0.925 0.835175129175 0.966048179194 35 iron ion binding(GO:0005506) 17006, 1222, 151, 11 1.014 0.88952808533 0.991243270923 151 copper ion binding(GO:0005507) 17006, 1863, 59, 13 2.011 0.0577162017087 0.408361892912 59 G protein-coupled serotonin receptor activity(GO:0004993) 17006, 464, 33, 1 1.111 0.803847147258 0.950779632485 33 glucosidase activity(GO:0015926) 17006, 735, 15, 3 4.627 0.0813735197714 0.474908734033 15 mitogen-activated protein kinase binding(GO:0051019) 17006, 11, 28, 1 55.214 0.0754473227332 0.469500508334 28 protein kinase A binding(GO:0051018) 17006, 1618, 49, 8 1.716 0.293416167206 0.735062494398 49 exogenous protein binding(GO:0140272) 17006, 1746, 76, 15 1.922 0.0608616259815 0.419133730926 76 signaling pattern recognition receptor activity(GO:0008329) 17006, 1681, 20, 3 1.517 0.518500224679 0.844743089721 20 methyl-CpG binding(GO:0008327) 17006, 1976, 25, 1 0.344 0.954543034174 1.0 25 MHC protein binding(GO:0042287) 17006, 1341, 29, 2 0.875 0.839797933123 0.966048179194 29 microtubule minus-end binding(GO:0051011) 17006, 0, 11, 0 0.0 1.0 1.0 11 xylosyltransferase activity(GO:0042285) 17006, 1664, 11, 2 1.858 0.420982010101 0.814304198748 11 lipid binding(GO:0008289) 17006, 1974, 734, 106 1.244 0.09590643958 0.497845990382 734 actin filament binding(GO:0051015) 17006, 431, 192, 19 3.905 7.98593610474e-06 0.00206236799905 192 peptide receptor activity(GO:0001653) 17006, 32, 151, 1 3.519 0.66399878749 0.900688262904 151 cofactor binding(GO:0048037) 17006, 325, 497, 17 1.79 0.12670394261 0.566602479291 497 cholesterol transporter activity(GO:0017127) 17006, 1955, 21, 2 0.828 0.818791437084 0.954716720116 21 monocarboxylic acid binding(GO:0033293) 17006, 1576, 73, 8 1.183 0.720595762642 0.919617906285 73 quinone binding(GO:0048038) 17006, 46, 16, 1 23.106 0.123465457656 0.566602479291 16 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) 17006, 697, 12, 1 2.033 0.528854621145 0.844743089721 12 racemase and epimerase activity(GO:0016854) 17006, 1085, 19, 2 1.65 0.543216871177 0.853404342611 19 isomerase activity(GO:0016853) 17006, 1174, 157, 15 1.384 0.463123889059 0.821849554378 157 cullin family protein binding(GO:0097602) 17006, 529, 18, 2 3.572 0.250308517556 0.711021691352 18 ephrin receptor activity(GO:0005003) 17006, 1369, 19, 2 1.308 0.634125105769 0.891943663175 19 alkali metal ion binding(GO:0031420) 17006, 1837, 15, 4 2.469 0.177064831907 0.624259287918 15 IgG binding(GO:0019864) 17006, 0, 11, 0 0.0 1.0 1.0 11 cis-trans isomerase activity(GO:0016859) 17006, 219, 44, 2 3.53 0.327285647436 0.746326873734 44 G protein-coupled neurotransmitter receptor activity(GO:0099528) 17006, 464, 40, 2 1.833 0.589341672779 0.880207012751 40 cysteine-type endopeptidase activity(GO:0004197) 17006, 1064, 120, 10 1.332 0.601882394534 0.883159820389 120 inositol tetrakisphosphate phosphatase activity(GO:0052743) 17006, 1213, 11, 2 2.549 0.3082059381 0.735062494398 11 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)(GO:0102568) 17006, 1497, 21, 2 1.082 0.717877735712 0.918461791404 21 RNA polymerase II general transcription initiation factor activity(GO:0016251) 17006, 1533, 12, 1 0.924 0.694065731748 0.913316761564 12 calcium-dependent cysteine-type endopeptidase activity(GO:0004198) 17006, 1982, 17, 4 2.019 0.285333645037 0.734425148506 17 ATPase activity, coupled to movement of substances(GO:0043492) 17006, 124, 134, 2 2.047 0.661754440923 0.900688262904 134 peptide hormone binding(GO:0017046) 17006, 32, 49, 2 21.691 0.0244070318556 0.283286111312 49 phospholipid scramblase activity(GO:0017128) 17006, 0, 11, 0 0.0 1.0 1.0 11 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645) 17006, 53, 26, 2 24.682 0.0150149689187 0.228232607772 26 SH3 domain binding(GO:0017124) 17006, 1640, 127, 16 1.306 0.518863558447 0.844743089721 127 Rho GTPase binding(GO:0017048) 17006, 261, 178, 6 2.196 0.285780080743 0.734425148506 178 GTP-Rho binding(GO:0017049) 17006, 33, 19, 1 27.123 0.115019419457 0.548549390736 19 peptide antigen binding(GO:0042605) 17006, 182, 25, 1 3.738 0.460940197889 0.821849554378 25 RNA polymerase III activity(GO:0001056) 17006, 766, 16, 1 1.388 0.656875801911 0.900451079235 16 phosphatidylinositol monophosphate phosphatase activity(GO:0052744) 17006, 0, 16, 0 0.0 1.0 1.0 16 RNA polymerase I activity(GO:0001054) 17006, 0, 12, 0 0.0 1.0 1.0 12 RNA polymerase II activity(GO:0001055) 17006, 1135, 11, 1 1.362 0.587438444965 0.880207012751 11 RNA polymerase II CTD heptapeptide repeat kinase activity(GO:0008353) 17006, 76, 17, 1 13.163 0.187615783029 0.637280604303 17 oligosaccharide binding(GO:0070492) 17006, 0, 15, 0 0.0 1.0 1.0 15 FAD binding(GO:0071949) 17006, 182, 30, 3 9.344 0.0216417946356 0.279449673233 30 repressing transcription factor binding(GO:0070491) 17006, 187, 70, 4 5.197 0.0458988094676 0.365498959845 70 oxidized DNA binding(GO:0032356) 17006, 1750, 11, 1 0.883 0.701304828214 0.913553452137 11 proline-rich region binding(GO:0070064) 17006, 189, 18, 1 4.999 0.361873901109 0.782174437659 18 RNA polymerase binding(GO:0070063) 17006, 221, 59, 2 2.608 0.475061222035 0.826262147787 59 nucleotide transmembrane transporter activity(GO:0015215) 17006, 848, 19, 4 4.222 0.0508096950486 0.38878825915 19 purine nucleotide transmembrane transporter activity(GO:0015216) 17006, 1430, 15, 4 3.171 0.0968816820723 0.500393887904 15 structural constituent of ribosome(GO:0003735) 17006, 495, 161, 5 1.067 0.882111332281 0.984442898321 161 secondary active monocarboxylate transmembrane transporter activity(GO:0015355) 17006, 237, 11, 1 6.523 0.269373042821 0.719024168564 11 chloride channel regulator activity(GO:0017081) 17006, 131, 16, 1 8.114 0.262425152332 0.711021691352 16 platelet-derived growth factor binding(GO:0048407) 17006, 295, 11, 1 5.241 0.30097442699 0.735062494398 11 mRNA 3'-UTR binding(GO:0003730) 17006, 1702, 78, 8 1.025 0.843071904295 0.966991054018 78 FMN binding(GO:0010181) 17006, 0, 15, 0 0.0 1.0 1.0 15 aryl sulfotransferase activity(GO:0004062) 17006, 0, 12, 0 0.0 1.0 1.0 12 arylsulfatase activity(GO:0004065) 17006, 519, 12, 2 5.461 0.128750064746 0.568921958917 12 myosin heavy chain binding(GO:0032036) 17006, 84, 12, 2 33.742 0.00699353388245 0.16614791553 12 kinase inhibitor activity(GO:0019210) 17006, 1040, 66, 6 1.487 0.54111634419 0.853404342611 66 deacetylase activity(GO:0019213) 17006, 1010, 60, 6 1.684 0.420391745981 0.814304198748 60 G-protein beta/gamma-subunit complex binding(GO:0031683) 17006, 179, 18, 1 5.278 0.352027515528 0.777017999018 18 intermediate filament binding(GO:0019215) 17006, 196, 15, 1 5.784 0.310249029581 0.735062494398 15 GTPase activity(GO:0003924) 17006, 1401, 295, 25 1.029 0.897140115658 0.997573454763 295 voltage-gated sodium channel activity(GO:0005248) 17006, 1667, 19, 2 1.074 0.707093361914 0.916471070084 19 potassium:proton antiporter activity(GO:0015386) 17006, 1279, 11, 1 1.209 0.614099842018 0.890715387283 11 HMG box domain binding(GO:0071837) 17006, 1033, 16, 2 2.058 0.433617489817 0.821849554378 16 translation elongation factor activity(GO:0003746) 17006, 1190, 20, 4 2.858 0.141991169482 0.589063767369 20 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) 17006, 124, 34, 1 4.034 0.480616725953 0.831619895996 34 low-density lipoprotein particle receptor binding(GO:0050750) 17006, 1889, 21, 6 2.572 0.0849012111882 0.483573446836 21 nitric-oxide synthase binding(GO:0050998) 17006, 1974, 15, 5 2.872 0.0768443185499 0.47023778186 15 miRNA binding(GO:0035198) 17006, 1788, 30, 2 0.634 0.912833700075 1.0 30 ammonium transmembrane transporter activity(GO:0008519) 17006, 95, 32, 1 5.594 0.397556552587 0.808417163036 32 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) 17006, 1815, 21, 4 1.785 0.372806098248 0.790777617022 21 organic anion transmembrane transporter activity(GO:0008514) 17006, 1433, 212, 22 1.232 0.592240095247 0.880207012751 212 scavenger receptor activity(GO:0005044) 17006, 1681, 50, 3 0.607 0.964622979826 1.0 50 siRNA binding(GO:0035197) 17006, 1292, 11, 1 1.197 0.616506773697 0.890715387283 11 low-density lipoprotein particle receptor activity(GO:0005041) 17006, 1681, 13, 1 0.778 0.749159609812 0.929029864269 13 modified amino acid transmembrane transporter activity(GO:0072349) 17006, 34, 16, 1 31.261 0.100537762495 0.50734985939 16 peptidoglycan binding(GO:0042834) 17006, 982, 16, 1 1.082 0.718409610314 0.918461791404 16 ammonium ion binding(GO:0070405) 17006, 1536, 75, 7 1.033 0.839518015783 0.966048179194 75 demethylase activity(GO:0032451) 17006, 473, 39, 3 2.766 0.285807269796 0.734425148506 39 histone demethylase activity(GO:0032452) 17006, 392, 29, 2 2.992 0.351435970708 0.777017999018 29 histone demethylase activity (H3-K9 specific)(GO:0032454) 17006, 392, 14, 1 3.099 0.437909809233 0.821849554378 14 NAD+ binding(GO:0070403) 17006, 567, 16, 1 1.875 0.573423301627 0.872380369043 16 NADPH binding(GO:0070402) 17006, 838, 14, 2 2.899 0.291113960853 0.735062494398 14 alditol:NADP+ 1-oxidoreductase activity(GO:0004032) 17006, 0, 14, 0 0.0 1.0 1.0 14 alcohol dehydrogenase (NADP+) activity(GO:0008106) 17006, 1191, 23, 1 0.621 0.874114160881 0.983180024081 23 potassium channel activity(GO:0005267) 17006, 123, 124, 4 4.46 0.0831805994201 0.47900665778 124 aromatase activity(GO:0070330) 17006, 1222, 22, 1 0.633 0.863649811809 0.980384896263 22 cation channel activity(GO:0005261) 17006, 123, 320, 5 2.16 0.404640110099 0.811637347052 320 toxic substance binding(GO:0015643) 17006, 1680, 11, 1 0.92 0.688344426868 0.909439117345 11 leucine zipper domain binding(GO:0043522) 17006, 505, 11, 3 9.184 0.01400889255 0.228232607772 11 kinesin binding(GO:0019894) 17006, 601, 41, 3 2.07 0.435485323401 0.821849554378 41 polyubiquitin modification-dependent protein binding(GO:0031593) 17006, 1559, 50, 7 1.527 0.445320722959 0.821849554378 50 protein folding chaperone(GO:0044183) 17006, 664, 23, 3 3.341 0.176298548104 0.623962323985 23 amino acid binding(GO:0016597) 17006, 309, 60, 2 1.835 0.63278696678 0.891943663175 60 glycine binding(GO:0016594) 17006, 126, 15, 1 8.998 0.238016296675 0.706922066586 15 phospholipid transporter activity(GO:0005548) 17006, 85, 67, 1 2.986 0.631160863055 0.891943663175 67 odorant binding(GO:0005549) 17006, 0, 88, 0 0.0 1.0 1.0 88 cell adhesion molecule binding(GO:0050839) 17006, 1992, 474, 82 1.477 0.00276671045457 0.0840591735169 474 GTP-dependent protein binding(GO:0030742) 17006, 0, 22, 0 0.0 1.0 1.0 22 phosphatidylinositol-4,5-bisphosphate phosphatase activity(GO:0106019) 17006, 0, 12, 0 0.0 1.0 1.0 12 phosphatidylinositol-5-phosphate binding(GO:0010314) 17006, 1812, 15, 4 2.503 0.170969066263 0.623962323985 15 hyaluronic acid binding(GO:0005540) 17006, 1200, 23, 1 0.616 0.87488991536 0.983180024081 23 folic acid binding(GO:0005542) 17006, 1778, 12, 1 0.797 0.737730314916 0.921739698866 12 phospholipid binding(GO:0005543) 17006, 1955, 423, 67 1.378 0.0425408264306 0.357273769941 423 calcium-dependent phospholipid binding(GO:0005544) 17006, 1769, 56, 11 1.888 0.129959586233 0.568921958917 56 1-phosphatidylinositol binding(GO:0005545) 17006, 1107, 16, 2 1.92 0.466385685843 0.822090582663 16 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) 17006, 1938, 73, 12 1.442 0.394811056612 0.808417163036 73 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) 17006, 372, 38, 2 2.406 0.463831839499 0.821849554378 38 transferase activity, transferring one-carbon groups(GO:0016741) 17006, 2000, 227, 37 1.386 0.161363727817 0.619660709424 227 transferase activity, transferring acyl groups(GO:0016746) 17006, 917, 262, 20 1.416 0.364415733041 0.782622561812 262 bitter taste receptor activity(GO:0033038) 17006, 30, 24, 1 23.619 0.138491918477 0.582865053113 24 UDP-glycosyltransferase activity(GO:0008194) 17006, 83, 148, 2 2.769 0.53277868585 0.849321577906 148 proton-exporting ATPase activity(GO:0036442) 17006, 452, 32, 2 2.351 0.455136428852 0.821849554378 32 K63-linked polyubiquitin modification-dependent protein binding(GO:0070530) 17006, 871, 22, 1 0.887 0.801152874673 0.950779632485 22 cadherin binding involved in cell-cell adhesion(GO:0098641) 17006, 883, 19, 2 2.027 0.453482085449 0.821849554378 19 phospholipase activator activity(GO:0016004) 17006, 0, 11, 0 0.0 1.0 1.0 11 lipid transporter activity(GO:0005319) 17006, 163, 150, 2 1.391 0.827277030587 0.960120168398 150 metalloendopeptidase activity(GO:0004222) 17006, 1475, 110, 14 1.467 0.364270136584 0.782622561812 110 semaphorin receptor binding(GO:0030215) 17006, 1640, 23, 7 3.156 0.0226917989343 0.282201599296 23 sugar transmembrane transporter activity(GO:0051119) 17006, 1491, 27, 3 1.267 0.660405807665 0.900688262904 27 dicarboxylic acid transmembrane transporter activity(GO:0005310) 17006, 1676, 40, 9 2.283 0.0698142193112 0.458455131176 40 L-glutamate transmembrane transporter activity(GO:0005313) 17006, 1180, 14, 4 4.118 0.0468026602197 0.369062198527 14 AMP binding(GO:0016208) 17006, 943, 13, 2 2.774 0.303445034944 0.735062494398 13 inositol trisphosphate phosphatase activity(GO:0046030) 17006, 1774, 11, 2 1.743 0.449932326205 0.821849554378 11 NF-kappaB binding(GO:0051059) 17006, 0, 29, 0 0.0 1.0 1.0 29 helicase activity(GO:0004386) 17006, 1627, 152, 19 1.307 0.485790723486 0.833591058738 152 disulfide oxidoreductase activity(GO:0015036) 17006, 1945, 41, 5 1.066 0.774342406123 0.940250413334 41 RNA methyltransferase activity(GO:0008173) 17006, 532, 63, 3 1.522 0.658564192299 0.900688262904 63 N-methyltransferase activity(GO:0008170) 17006, 1976, 96, 22 1.972 0.0105850394098 0.209050083147 96 O-methyltransferase activity(GO:0008171) 17006, 1921, 24, 6 2.213 0.151036761598 0.601999705183 24 proton-transporting ATPase activity, rotational mechanism(GO:0046961) 17006, 452, 23, 2 3.272 0.304207105979 0.735062494398 23 tRNA methyltransferase activity(GO:0008175) 17006, 532, 34, 2 1.88 0.556390387116 0.86289366894 34 adenylate cyclase binding(GO:0008179) 17006, 264, 13, 1 4.955 0.338706111775 0.757418716885 13 laminin binding(GO:0043236) 17006, 1461, 29, 1 0.401 0.945895669078 1.0 29 oxygen binding(GO:0019825) 17006, 159, 35, 1 3.056 0.552024163933 0.858796628528 35 S100 protein binding(GO:0044548) 17006, 1995, 15, 8 4.546 0.000582048395045 0.0429468565772 15 postsynaptic neurotransmitter receptor activity(GO:0098960) 17006, 1320, 52, 4 0.991 0.84342588545 0.966991054018 52 Notch binding(GO:0005112) 17006, 0, 22, 0 0.0 1.0 1.0 22 fatty acid synthase activity(GO:0004312) 17006, 861, 11, 2 3.591 0.213248108839 0.673655340767 11 MAP kinase activity(GO:0004707) 17006, 1035, 14, 2 2.347 0.372763430741 0.790777617022 14 iron ion transmembrane transporter activity(GO:0005381) 17006, 1146, 11, 1 1.349 0.589475079462 0.880207012751 11 palmitoyl-CoA hydrolase activity(GO:0016290) 17006, 1075, 12, 2 2.637 0.314858765884 0.737644348616 12 zinc ion transmembrane transporter activity(GO:0005385) 17006, 1686, 20, 7 3.53 0.0107257061053 0.209050083147 20 ligand-gated calcium channel activity(GO:0099604) 17006, 1892, 27, 5 1.665 0.392916382764 0.808417163036 27 lipase activity(GO:0016298) 17006, 1101, 134, 13 1.498 0.377256722834 0.795318764668 134 MAP kinase kinase activity(GO:0004708) 17006, 11, 16, 1 96.625 0.0398232529266 0.354208787353 16 activin binding(GO:0048185) 17006, 1415, 14, 4 3.434 0.0759511164207 0.469805408758 14 aldo-keto reductase (NADP) activity(GO:0004033) 17006, 1191, 29, 1 0.492 0.932055396245 1.0 29 phosphatase activator activity(GO:0019211) 17006, 6, 16, 1 177.146 0.0241607825229 0.283286111312 16 Ral GTPase binding(GO:0017160) 17006, 1329, 15, 2 1.706 0.492661650712 0.83980113067 15 RNA polymerase III regulatory region DNA binding(GO:0001016) 17006, 758, 11, 1 2.04 0.51763742629 0.844743089721 11 general transcription initiation factor activity(GO:0140223) 17006, 1533, 20, 1 0.555 0.867266064689 0.980952531603 20 RNA polymerase II regulatory region DNA binding(GO:0001012) 17006, 406, 772, 31 1.682 0.0418329835984 0.354208787353 772 5'-3' RNA polymerase activity(GO:0034062) 17006, 260, 44, 1 1.487 0.766306145797 0.937740091323 44 DNA polymerase activity(GO:0034061) 17006, 1056, 31, 1 0.519 0.927196154521 1.0 31 endopeptidase regulator activity(GO:0061135) 17006, 1754, 181, 17 0.911 0.95940769543 1.0 181 GTPase binding(GO:0051020) 17006, 1579, 653, 83 1.369 0.0255793958299 0.287212129264 653 phosphatase inhibitor activity(GO:0019212) 17006, 1461, 44, 8 2.116 0.135389616459 0.578363316844 44 dopamine binding(GO:0035240) 17006, 0, 13, 0 0.0 1.0 1.0 13 aminoacyl-tRNA editing activity(GO:0002161) 17006, 937, 12, 3 4.537 0.0740932489718 0.469282612099 12 structural constituent of epidermis(GO:0030280) 17006, 0, 16, 0 0.0 1.0 1.0 16 cofactor transmembrane transporter activity(GO:0051184) 17006, 34, 22, 1 22.735 0.139374266497 0.582865053113 22 sialyltransferase activity(GO:0008373) 17006, 1731, 20, 7 3.439 0.0131280420902 0.228232607772 20 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) 17006, 401, 26, 2 3.262 0.309230141465 0.735062494398 26 transition metal ion binding(GO:0046914) 17006, 1351, 1069, 101 1.189 0.274859954882 0.720466987857 1069 phosphoric diester hydrolase activity(GO:0008081) 17006, 1407, 94, 9 1.157 0.751551947235 0.930059447969 94 hydrolase activity, acting on ether bonds(GO:0016801) 17006, 1643, 13, 1 0.796 0.742685802135 0.925445637642 13 dipeptidase activity(GO:0016805) 17006, 560, 16, 1 1.898 0.570429943292 0.870390149809 16 Wnt-activated receptor activity(GO:0042813) 17006, 972, 18, 3 2.916 0.203588706551 0.662579515723 18 protein-lipid complex binding(GO:0071814) 17006, 1681, 26, 1 0.389 0.94009356657 1.0 26 transferase activity, transferring amino-acyl groups(GO:0016755) 17006, 1355, 18, 2 1.395 0.600592147044 0.883159820389 18 oligopeptide binding(GO:1900750) 17006, 126, 12, 1 11.247 0.186229399234 0.634900889136 12 phospholipase A1 activity(GO:0008970) 17006, 1013, 11, 2 3.052 0.262860632195 0.711021691352 11 chromatin binding(GO:0003682) 17006, 92, 523, 7 2.474 0.174025705887 0.623962323985 523 tumor necrosis factor receptor superfamily binding(GO:0032813) 17006, 1064, 47, 1 0.34 0.982200954669 1.0 47 photoreceptor activity(GO:0009881) 17006, 1379, 17, 1 0.725 0.797071940693 0.948589072277 17 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) 17006, 13, 14, 2 186.879 0.000280676411939 0.0263580666848 14 RNA cap binding(GO:0000339) 17006, 279, 20, 1 3.048 0.483968222278 0.833231956021 20 filamin binding(GO:0031005) 17006, 17, 13, 1 76.95 0.0459969649369 0.365498959845 13 poly(A)-specific ribonuclease activity(GO:0004535) 17006, 790, 13, 2 3.312 0.24417670823 0.711021691352 13 manganese ion binding(GO:0030145) 17006, 1664, 61, 5 0.838 0.921902609407 1.0 61 Ras GTPase binding(GO:0017016) 17006, 1974, 541, 85 1.354 0.0265818796446 0.291772849872 541 lysophospholipase activity(GO:0004622) 17006, 1013, 24, 5 3.497 0.0519069829383 0.391306945372 24 tRNA binding(GO:0000049) 17006, 532, 58, 5 2.756 0.156258462711 0.610424663013 58 translation activator activity(GO:0008494) 17006, 0, 13, 0 0.0 1.0 1.0 13 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) 17006, 1084, 13, 3 3.62 0.12325701131 0.566602479291 13 amyloid-beta binding(GO:0001540) 17006, 371, 79, 1 0.58 0.9666424344 1.0 79 fibroblast growth factor binding(GO:0017134) 17006, 835, 23, 4 3.542 0.0893779995276 0.487291421467 23 calcium-dependent protein kinase activity(GO:0010857) 17006, 11, 12, 1 128.833 0.0289765160032 0.308584959086 12 G protein-coupled amine receptor activity(GO:0008227) 17006, 1237, 58, 5 1.185 0.738819429488 0.921739698866 58 potassium-transporting ATPase activity(GO:0008556) 17006, 319, 11, 1 4.846 0.313881099812 0.737644348616 11 RNA polymerase II transcription factor binding(GO:0001085) 17006, 187, 53, 3 5.148 0.100635907051 0.50734985939 53 phosphatidylinositol phosphate phosphatase activity(GO:0052866) 17006, 561, 30, 1 1.01 0.811798292209 0.950779632485 30 P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) 17006, 124, 126, 1 1.088 0.914440976196 1.0 126 guanyl nucleotide binding(GO:0019001) 17006, 1648, 393, 47 1.234 0.39679215808 0.808417163036 393 sodium channel regulator activity(GO:0017080) 17006, 263, 35, 4 7.39 0.0111076881323 0.210600091419 35 GDP binding(GO:0019003) 17006, 140, 61, 1 1.991 0.72930359545 0.921739698866 61 tau-protein kinase activity(GO:0050321) 17006, 1488, 22, 3 1.558 0.519437674633 0.844743089721 22 alpha-tubulin binding(GO:0043014) 17006, 429, 33, 4 4.805 0.0449967556317 0.365498959845 33 gamma-tubulin binding(GO:0043015) 17006, 252, 25, 1 2.699 0.548902951022 0.856520767984 25 protein dimerization activity(GO:0046983) 17006, 306, 1288, 39 1.683 0.0151176404802 0.228232607772 1288 protein heterodimerization activity(GO:0046982) 17006, 306, 474, 14 1.641 0.299151980769 0.735062494398 474 calcium-activated potassium channel activity(GO:0015269) 17006, 834, 15, 1 1.359 0.662201755427 0.900688262904 15 transmembrane receptor protein serine/threonine kinase binding(GO:0070696) 17006, 1558, 17, 4 2.568 0.169045879327 0.623962323985 17 translation initiation factor activity(GO:0003743) 17006, 31, 52, 1 10.55 0.3012585489 0.735062494398 52 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016796) 17006, 270, 55, 1 1.145 0.847385935058 0.970454180615 55 phosphatase activity(GO:0016791) 17006, 1896, 278, 36 1.162 0.630924681547 0.891943663175 278 cell adhesion mediator activity(GO:0098631) 17006, 1516, 59, 11 2.091 0.0778462388894 0.47023778186 59 cell-cell adhesion mediator activity(GO:0098632) 17006, 1516, 50, 11 2.468 0.0249756102349 0.285872675215 50 calcium-dependent protein binding(GO:0048306) 17006, 1995, 61, 13 1.817 0.11483839723 0.548549390736 61 chemokine binding(GO:0019956) 17006, 1942, 32, 8 2.189 0.100684144409 0.50734985939 32 C-C chemokine binding(GO:0019957) 17006, 1818, 24, 5 1.949 0.272047868021 0.720123263067 24 cytokine binding(GO:0019955) 17006, 1944, 128, 21 1.435 0.264602882122 0.711809315708 128 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) 17006, 1390, 25, 4 1.958 0.33874873882 0.757418716885 25 hydrolase activity, acting on glycosyl bonds(GO:0016798) 17006, 979, 120, 9 1.303 0.650357173577 0.898965850169 120 endodeoxyribonuclease activity(GO:0004520) 17006, 62, 41, 1 6.69 0.37537166936 0.792963056132 41 phospholipase inhibitor activity(GO:0004859) 17006, 302, 13, 1 4.332 0.362692696649 0.782174437659 13 E-box binding(GO:0070888) 17006, 71, 50, 3 14.371 0.00806732187613 0.177309436129 50 enzyme inhibitor activity(GO:0004857) 17006, 12, 371, 1 3.82 0.713334515761 0.918461791404 371 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) 17006, 1147, 28, 5 2.648 0.133807083934 0.577774832791 28 oxidoreductase activity(GO:0016491) 17006, 520, 732, 28 1.251 0.586829799255 0.880207012751 732 exodeoxyribonuclease activity(GO:0004529) 17006, 62, 25, 1 10.972 0.240495855505 0.709806339247 25 phosphatidylethanolamine binding(GO:0008429) 17006, 1303, 11, 3 3.559 0.115797183553 0.548549390736 11 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) 17006, 16, 40, 1 26.572 0.148883222827 0.598429452064 40 Hsp70 protein binding(GO:0030544) 17006, 1862, 40, 1 0.228 0.990875794679 1.0 40 receptor regulator activity(GO:0030545) 17006, 37, 519, 3 2.657 0.490820973423 0.838046389332 519 receptor activator activity(GO:0030546) 17006, 0, 12, 0 0.0 1.0 1.0 12 receptor inhibitor activity(GO:0030547) 17006, 1881, 38, 4 0.952 0.830044195705 0.961250733367 38 endoribonuclease activity(GO:0004521) 17006, 62, 61, 1 4.497 0.511506111601 0.844743089721 61 dynein intermediate chain binding(GO:0045505) 17006, 1626, 29, 2 0.721 0.88121510549 0.984442898321 29 lipopolysaccharide binding(GO:0001530) 17006, 1241, 34, 1 0.403 0.961474374286 1.0 34 phosphatidylinositol bisphosphate kinase activity(GO:0052813) 17006, 13, 74, 1 17.678 0.233107671264 0.7020414706 74 lysine-acetylated histone binding(GO:0070577) 17006, 76, 19, 1 11.777 0.211764844743 0.673086414214 19 wide pore channel activity(GO:0022829) 17006, 1936, 24, 4 1.464 0.521285596178 0.844743089721 24 protease binding(GO:0002020) 17006, 1193, 125, 15 1.711 0.160980848387 0.619660709424 125 transmitter-gated ion channel activity(GO:0022824) 17006, 1320, 61, 3 0.634 0.967615413154 1.0 61 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) 17006, 1945, 11, 1 0.795 0.73740880339 0.921739698866 11 ligase activity, forming carbon-sulfur bonds(GO:0016877) 17006, 699, 40, 1 0.608 0.926130197505 1.0 40 phosphatidylserine binding(GO:0001786) 17006, 366, 59, 3 2.363 0.399719306971 0.810021937041 59 potassium ion antiporter activity(GO:0022821) 17006, 1279, 16, 1 0.831 0.761189671435 0.9347027937 16 phosphotyrosine residue binding(GO:0001784) 17006, 13, 40, 1 32.704 0.12640081967 0.566602479291 40 mismatch repair complex binding(GO:0032404) 17006, 1505, 11, 1 1.027 0.655943423505 0.900451079235 11 SH2 domain binding(GO:0042169) 17006, 27, 34, 1 18.525 0.182906138763 0.627714423064 34 GTPase activating protein binding(GO:0032794) 17006, 0, 14, 0 0.0 1.0 1.0 14 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667) 17006, 1945, 59, 5 0.741 0.952945479733 1.0 59 protein tyrosine/serine/threonine phosphatase activity(GO:0008138) 17006, 145, 45, 1 2.606 0.62418438632 0.891773412314 45 nuclear localization sequence binding(GO:0008139) 17006, 508, 24, 4 5.579 0.0251833624826 0.285872675215 24 amide binding(GO:0033218) 17006, 32, 352, 2 3.02 0.558849342523 0.864208638962 352 phosphatidic acid binding(GO:0070300) 17006, 931, 19, 5 4.807 0.0141165335288 0.228232607772 19 intracellular ligand-gated ion channel activity(GO:0005217) 17006, 1892, 33, 6 1.634 0.380567130489 0.797842533823 33 acetylcholine binding(GO:0042166) 17006, 0, 17, 0 0.0 1.0 1.0 17 ubiquitin-like protein conjugating enzyme binding(GO:0044390) 17006, 1859, 37, 7 1.731 0.299307607097 0.735062494398 37 SUMO transferase activity(GO:0019789) 17006, 219, 25, 1 3.106 0.508834653014 0.844743089721 25 phospholipase binding(GO:0043274) 17006, 0, 14, 0 0.0 1.0 1.0 14 peptide hormone receptor binding(GO:0051428) 17006, 394, 21, 2 4.111 0.226046517023 0.688808413229 21 hormone receptor binding(GO:0051427) 17006, 394, 186, 17 3.945 2.78946346811e-05 0.00445453671207 186 peptidyl-proline dioxygenase activity(GO:0031543) 17006, 771, 12, 2 3.676 0.210077920848 0.670144382069 12 signal sequence binding(GO:0005048) 17006, 508, 45, 4 2.976 0.175174612552 0.623962323985 45 ubiquitin conjugating enzyme binding(GO:0031624) 17006, 1859, 31, 6 1.771 0.310159893249 0.735062494398 31 protein binding involved in heterotypic cell-cell adhesion(GO:0086080) 17006, 1516, 13, 6 5.177 0.00210558375358 0.0750023454293 13 sialic acid binding(GO:0033691) 17006, 0, 11, 0 0.0 1.0 1.0 11 threonine-type endopeptidase activity(GO:0004298) 17006, 0, 21, 0 0.0 1.0 1.0 21 frizzled binding(GO:0005109) 17006, 1612, 39, 6 1.623 0.407768421383 0.812324557007 39 acetyltransferase activity(GO:0016407) 17006, 50, 108, 1 3.149 0.663981954309 0.900688262904 108 thiolester hydrolase activity(GO:0016790) 17006, 1075, 34, 4 1.861 0.399914025064 0.810021937041 34 calmodulin binding(GO:0005516) 17006, 29, 198, 3 8.885 0.0387024788105 0.347649222707 198 olfactory receptor activity(GO:0004984) 17006, 137, 403, 1 0.308 0.999662576559 1.0 403 inorganic anion exchanger activity(GO:0005452) 17006, 134, 15, 1 8.461 0.24651743297 0.711021691352 15 signaling receptor binding(GO:0005102) 17006, 68, 1555, 13 2.091 0.0914100969731 0.489576697981 1555 monovalent cation:proton antiporter activity(GO:0005451) 17006, 1279, 13, 1 1.023 0.68067353912 0.903773478035 13 fibroblast growth factor receptor binding(GO:0005104) 17006, 399, 26, 2 3.279 0.307381150796 0.735062494398 26 C-acyltransferase activity(GO:0016408) 17006, 983, 20, 3 2.595 0.256455294878 0.711021691352 20 peptide alpha-N-acetyltransferase activity(GO:0004596) 17006, 0, 12, 0 0.0 1.0 1.0 12 aminopeptidase activity(GO:0004177) 17006, 1665, 46, 8 1.776 0.259289606968 0.711021691352 46 muscle alpha-actinin binding(GO:0051371) 17006, 355, 16, 4 11.976 0.00140311172467 0.0536820152437 16 sulfuric ester hydrolase activity(GO:0008484) 17006, 519, 17, 2 3.855 0.224509109178 0.688808413229 17 polysaccharide binding(GO:0030247) 17006, 422, 22, 2 3.664 0.263445711418 0.711021691352 22 carbohydrate binding(GO:0030246) 17006, 1589, 270, 27 1.07 0.839352184305 0.966048179194 270 nucleocytoplasmic carrier activity(GO:0140142) 17006, 1878, 18, 2 1.006 0.732016651872 0.921739698866 18 mismatched DNA binding(GO:0030983) 17006, 1750, 14, 4 2.776 0.129364630299 0.568921958917 14 DNA helicase activity(GO:0003678) 17006, 813, 53, 4 1.579 0.559859929355 0.864477290021 53 neurexin family protein binding(GO:0042043) 17006, 929, 13, 2 2.816 0.297844696592 0.735062494398 13 protein kinase A catalytic subunit binding(GO:0034236) 17006, 966, 13, 4 5.417 0.019250277733 0.25825372595 13 protein kinase A regulatory subunit binding(GO:0034237) 17006, 966, 20, 3 2.641 0.249816583256 0.711021691352 20 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) 17006, 1292, 15, 1 0.878 0.738682901002 0.921739698866 15 bioactive lipid receptor activity(GO:0045125) 17006, 913, 14, 2 2.661 0.32166970539 0.741707155508 14 annealing activity(GO:0097617) 17006, 413, 13, 1 3.167 0.420076677417 0.814304198748 13 titin binding(GO:0031432) 17006, 329, 14, 5 18.461 3.01856311563e-05 0.00445453671207 14 carbon-sulfur lyase activity(GO:0016846) 17006, 736, 15, 1 1.54 0.622016446041 0.891403190854 15 carbon-nitrogen lyase activity(GO:0016840) 17006, 391, 13, 1 3.346 0.408914588232 0.812324557007 13 mitogen-activated protein kinase kinase kinase binding(GO:0031435) 17006, 1110, 18, 2 1.702 0.526473941141 0.844743089721 18 mitogen-activated protein kinase kinase binding(GO:0031434) 17006, 1047, 14, 1 1.16 0.672355025916 0.901521222362 14 metallocarboxypeptidase activity(GO:0004181) 17006, 1192, 30, 2 0.951 0.809832070672 0.950779632485 30 carboxypeptidase activity(GO:0004180) 17006, 1192, 47, 5 1.518 0.525985654398 0.844743089721 47 phosphorus-oxygen lyase activity(GO:0016849) 17006, 231, 23, 2 6.402 0.129976362347 0.568921958917 23 transmembrane transporter activity(GO:0022857) 17006, 303, 1058, 24 1.273 0.612201973981 0.890715387283 1058 transporter activity(GO:0005215) 17006, 303, 1260, 26 1.158 0.796240289247 0.948589072277 1260 transmembrane receptor protein serine/threonine kinase activity(GO:0004675) 17006, 1228, 18, 5 3.847 0.0316645004002 0.320680675622 18 protein serine/threonine kinase activity(GO:0004674) 17006, 131, 456, 11 3.132 0.0112129767938 0.210600091419 456 ligand-gated anion channel activity(GO:0099095) 17006, 626, 19, 1 1.43 0.666738195551 0.900688262904 19 ligand-gated cation channel activity(GO:0099094) 17006, 95, 106, 3 5.066 0.126032225732 0.566602479291 106 telomeric DNA binding(GO:0042162) 17006, 1236, 38, 6 2.172 0.193675353364 0.643900381858 38 channel regulator activity(GO:0016247) 17006, 264, 146, 7 3.088 0.0557895443417 0.400901900197 146 GABA-gated chloride ion channel activity(GO:0022851) 17006, 626, 12, 1 2.264 0.496078207213 0.842884565816 12 transcription factor binding(GO:0008134) 17006, 837, 642, 54 1.709 0.00155638997077 0.0574196728502 642 structural constituent of nuclear pore(GO:0017056) 17006, 542, 27, 3 3.486 0.17182758884 0.623962323985 27 WW domain binding(GO:0050699) 17006, 24, 32, 1 22.143 0.157621980446 0.610424663013 32 ATP-dependent DNA helicase activity(GO:0004003) 17006, 813, 39, 4 2.145 0.325413054846 0.745916947999 39 adenosine deaminase activity(GO:0004000) 17006, 896, 12, 2 3.163 0.25508800747 0.711021691352 12 peptidase regulator activity(GO:0061134) 17006, 1754, 219, 20 0.885 0.976570429649 1.0 219 nucleoside-diphosphatase activity(GO:0017110) 17006, 802, 14, 2 3.029 0.276545108215 0.720466987857 14 TFIID-class transcription factor complex binding(GO:0001094) 17006, 1716, 11, 2 1.802 0.434604462411 0.821849554378 11 Rab guanyl-nucleotide exchange factor activity(GO:0017112) 17006, 174, 53, 3 5.532 0.0869597128719 0.485742494715 53 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) 17006, 585, 13, 1 2.236 0.504022697561 0.844743089721 13 DNA-(apurinic or apyrimidinic site) endonuclease activity(GO:0003906) 17006, 1390, 13, 3 2.823 0.190012029163 0.637280604303 13 oxidoreductase activity, acting on the aldehyde or oxo group of donors(GO:0016903) 17006, 1817, 45, 7 1.456 0.479677284054 0.831386970517 45 neurotransmitter binding(GO:0042165) 17006, 237, 55, 2 2.609 0.469549663238 0.822109834111 55 core promoter binding(GO:0001047) 17006, 484, 54, 5 3.253 0.0925355142465 0.489576697981 54 core promoter sequence-specific DNA binding(GO:0001046) 17006, 484, 44, 5 3.993 0.0445819903816 0.365498959845 44 peptide transmembrane transporter activity(GO:1904680) 17006, 68, 32, 1 7.815 0.320676596319 0.741707155508 32 promoter-specific chromatin binding(GO:1990841) 17006, 863, 48, 5 2.053 0.304848512999 0.735062494398 48 protein self-association(GO:0043621) 17006, 28, 56, 1 10.846 0.300341087093 0.735062494398 56 insulin-like growth factor I binding(GO:0031994) 17006, 1091, 12, 3 3.897 0.103364919281 0.518329910764 12 macromolecule transmembrane transporter activity(GO:0022884) 17006, 759, 23, 1 0.974 0.783997115967 0.943903287639 23 thioesterase binding(GO:0031996) 17006, 0, 11, 0 0.0 1.0 1.0 11 DNA-binding transcription factor activity(GO:0003700) 17006, 803, 1696, 105 1.311 0.0321407018078 0.322343155024 1696 poly-purine tract binding(GO:0070717) 17006, 1604, 29, 7 2.559 0.0701218884083 0.458455131176 29 translation repressor activity, mRNA regulatory element binding(GO:0000900) 17006, 199, 14, 1 6.104 0.294954642089 0.735062494398 14 sodium-independent organic anion transmembrane transporter activity(GO:0015347) 17006, 0, 16, 0 0.0 1.0 1.0 16 steroid hormone receptor activity(GO:0003707) 17006, 1105, 56, 7 1.924 0.254379162313 0.711021691352 56 signaling adaptor activity(GO:0035591) 17006, 241, 79, 4 3.573 0.13367492944 0.577774832791 79 scaffold protein binding(GO:0097110) 17006, 468, 57, 6 3.825 0.0300005492263 0.314203307592 57 retinoic acid receptor binding(GO:0042974) 17006, 318, 25, 3 6.417 0.0480152183557 0.372930229785 25 peroxisome proliferator activated receptor binding(GO:0042975) 17006, 288, 11, 2 10.736 0.0448683940598 0.365498959845 11 calcium channel inhibitor activity(GO:0019855) 17006, 978, 12, 3 4.347 0.0813193286885 0.474908734033 12 adenyl-nucleotide exchange factor activity(GO:0000774) 17006, 429, 11, 1 3.604 0.371301730873 0.790777617022 11 3'-5'-exodeoxyribonuclease activity(GO:0008296) 17006, 0, 13, 0 0.0 1.0 1.0 13 galactosyltransferase activity(GO:0008378) 17006, 72, 35, 1 6.748 0.359568983814 0.780325126639 35 adrenergic receptor binding(GO:0031690) 17006, 51, 19, 2 35.1 0.00754532399693 0.169441732366 19 exonuclease activity(GO:0004527) 17006, 270, 83, 3 2.277 0.450472543855 0.821849554378 83 monooxygenase activity(GO:0004497) 17006, 16, 100, 1 10.629 0.347574502811 0.773802718543 100 molecular transducer activity(GO:0060089) 17006, 179, 1529, 14 0.87 0.994902810409 1.0 1529 icosanoid receptor activity(GO:0004953) 17006, 0, 14, 0 0.0 1.0 1.0 14 RNA polymerase II-specific DNA-binding transcription factor binding(GO:0061629) 17006, 338, 266, 17 3.216 0.000396961903484 0.0340655293888 266 ankyrin binding(GO:0030506) 17006, 1667, 20, 6 3.06 0.0416360577088 0.354208787353 20 interleukin-1 receptor binding(GO:0005149) 17006, 1863, 15, 2 1.217 0.635891000504 0.891943663175 15 SH3/SH2 adaptor activity(GO:0005070) 17006, 241, 53, 3 3.994 0.166262311362 0.623962323985 53 actin binding(GO:0003779) 17006, 355, 423, 30 3.397 1.52634353053e-07 5.2557095568e-05 423 sodium ion transmembrane transporter activity(GO:0015081) 17006, 1967, 151, 20 1.145 0.714919195024 0.918461791404 151 ribonuclease P activity(GO:0004526) 17006, 1663, 11, 3 2.789 0.181374342193 0.627631006816 11 anion transmembrane transporter activity(GO:0008509) 17006, 1676, 334, 36 1.094 0.790704023774 0.946462637959 334 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) 17006, 1817, 36, 7 1.82 0.256537076234 0.711021691352 36 hormone binding(GO:0042562) 17006, 86, 102, 3 5.816 0.0933655464687 0.489576697981 102 aspartic-type peptidase activity(GO:0070001) 17006, 1799, 25, 1 0.378 0.941634096055 1.0 25 cyclin-dependent protein kinase activity(GO:0097472) 17006, 1014, 37, 4 1.813 0.425783874849 0.817536696504 37 dynein light intermediate chain binding(GO:0051959) 17006, 1626, 29, 2 0.721 0.88121510549 0.984442898321 29 m7G(5')pppN diphosphatase activity(GO:0050072) 17006, 643, 11, 1 2.404 0.475920598193 0.826262147787 11 metalloaminopeptidase activity(GO:0070006) 17006, 382, 21, 2 4.24 0.216712129282 0.682511065696 21 metal ion transmembrane transporter activity(GO:0046873) 17006, 400, 444, 17 1.628 0.238149931434 0.706922066586 444 ephrin receptor binding(GO:0046875) 17006, 1359, 27, 3 1.39 0.611472037394 0.890715387283 27 structural constituent of eye lens(GO:0005212) 17006, 1428, 20, 2 1.191 0.676402515623 0.902743925889 20 epidermal growth factor receptor binding(GO:0005154) 17006, 1052, 33, 2 0.98 0.811633174396 0.950779632485 33 GDP-dissociation inhibitor activity(GO:0005092) 17006, 0, 14, 0 0.0 1.0 1.0 14 insulin-like growth factor receptor binding(GO:0005159) 17006, 13, 16, 1 81.76 0.0453979535713 0.365498959845 16 insulin receptor binding(GO:0005158) 17006, 13, 22, 1 59.462 0.0654953430347 0.445109798387 22 GTPase activator activity(GO:0005096) 17006, 261, 279, 12 2.802 0.0146030619796 0.228232607772 279 organic acid:sodium symporter activity(GO:0005343) 17006, 1676, 29, 6 2.099 0.192045689326 0.642016819009 29 GTPase inhibitor activity(GO:0005095) 17006, 1734, 14, 3 2.102 0.312910648901 0.737644348616 14 kinase binding(GO:0019900) 17006, 1273, 720, 90 1.67 2.26186434379e-05 0.00445453671207 720 protein phosphatase binding(GO:0019903) 17006, 231, 137, 9 4.836 0.00129999027859 0.0536820152437 137 phosphatase binding(GO:0019902) 17006, 1602, 182, 34 1.983 0.00103830994945 0.0491496331736 182 syntaxin binding(GO:0019905) 17006, 799, 71, 3 0.899 0.90149968398 0.999194392223 71 protein domain specific binding(GO:0019904) 17006, 564, 689, 34 1.488 0.124224187102 0.566602479291 689 ADP binding(GO:0043531) 17006, 319, 39, 1 1.367 0.775844151575 0.940250413334 39 G protein-coupled purinergic nucleotide receptor activity(GO:0045028) 17006, 1338, 15, 4 3.389 0.0834667941921 0.47900665778 15 ribosomal large subunit binding(GO:0043023) 17006, 498, 13, 1 2.627 0.462307419587 0.821849554378 13 protein serine/threonine kinase activator activity(GO:0043539) 17006, 264, 29, 2 4.443 0.223117349706 0.688808413229 29 lamin binding(GO:0005521) 17006, 431, 15, 1 2.63 0.484895218934 0.833438870481 15 histone acetyltransferase binding(GO:0035035) 17006, 1332, 29, 4 1.761 0.416779071123 0.814304198748 29 fatty acid derivative binding(GO:1901567) 17006, 1141, 27, 3 1.656 0.509611885468 0.844743089721 27 Hsp90 protein binding(GO:0051879) 17006, 1996, 39, 6 1.311 0.597181220375 0.881268858068 39 ribosomal small subunit binding(GO:0043024) 17006, 31, 16, 1 34.286 0.0930545918767 0.489576697981 16 amino acid:cation symporter activity(GO:0005416) 17006, 1419, 21, 4 2.283 0.242665962008 0.711021691352 21 chemorepellent activity(GO:0045499) 17006, 961, 27, 5 3.277 0.0683800455289 0.455719916331 27 nucleoside diphosphate kinase activity(GO:0004550) 17006, 684, 18, 1 1.381 0.667734795041 0.900688262904 18 nucleotide diphosphatase activity(GO:0004551) 17006, 643, 18, 1 1.469 0.651815509948 0.898965850169 18 transferase activity, transferring glycosyl groups(GO:0016757) 17006, 1822, 290, 39 1.255 0.38901914212 0.805324196011 290 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) 17006, 422, 96, 3 1.259 0.796055598154 0.948589072277 96 transferase activity, transferring hexosyl groups(GO:0016758) 17006, 1351, 217, 21 1.218 0.628938238579 0.891943663175 217 protein deacetylase activity(GO:0033558) 17006, 795, 46, 4 1.86 0.435974102737 0.821849554378 46 RNA polymerase II complex binding(GO:0000993) 17006, 76, 36, 1 6.216 0.380770928533 0.797842533823 36 mRNA 3'-UTR AU-rich region binding(GO:0035925) 17006, 1600, 14, 1 0.759 0.761877785378 0.9347027937 14 structural constituent of synapse(GO:0098918) 17006, 1885, 16, 3 1.692 0.439672271496 0.821849554378 16 zinc ion binding(GO:0008270) 17006, 1341, 807, 80 1.257 0.164389736244 0.623962323985 807 histone binding(GO:0042393) 17006, 76, 188, 2 2.38 0.621992386892 0.891403190854 188 neurotransmitter:sodium symporter activity(GO:0005328) 17006, 1180, 27, 3 1.601 0.528052134645 0.844743089721 27 arginine N-methyltransferase activity(GO:0016273) 17006, 79, 12, 1 17.939 0.136056712251 0.578381003108 12 ion channel regulator activity(GO:0099106) 17006, 264, 119, 6 3.248 0.0731916512208 0.466709726612 119 long-chain fatty acid transporter activity(GO:0005324) 17006, 1502, 12, 2 1.887 0.421735475634 0.814304198748 12 transforming growth factor beta-activated receptor activity(GO:0005024) 17006, 1228, 15, 5 4.616 0.0138651937422 0.228232607772 15 neurotransmitter transporter activity(GO:0005326) 17006, 1180, 54, 7 1.868 0.273882746819 0.720423134454 54 superoxide-generating NADPH oxidase activity(GO:0016175) 17006, 1865, 12, 2 1.52 0.518966084943 0.844743089721 12 lysine N-methyltransferase activity(GO:0016278) 17006, 1755, 62, 14 2.188 0.0259138873788 0.28783920067 62 phosphatidylinositol-3-phosphate binding(GO:0032266) 17006, 38, 37, 1 12.095 0.251648996928 0.711021691352 37 acid-amino acid ligase activity(GO:0016881) 17006, 126, 20, 1 6.748 0.308274647117 0.735062494398 20 protein-containing complex binding(GO:0044877) 17006, 84, 1065, 13 2.471 0.0283019476242 0.304540748914 1065 ATPase activity(GO:0016887) 17006, 843, 450, 29 1.3 0.447568272699 0.821849554378 450 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889) 17006, 1956, 12, 2 1.449 0.543593001599 0.853404342611 12 Ran GTPase binding(GO:0008536) 17006, 1878, 38, 10 2.383 0.0375279427172 0.343720048811 38 ATPase-coupled anion transmembrane transporter activity(GO:0043225) 17006, 698, 11, 1 2.215 0.501449980195 0.844743089721 11 ATPase coupled ion transmembrane transporter activity(GO:0042625) 17006, 452, 68, 3 1.66 0.616909479519 0.890715387283 68 CoA hydrolase activity(GO:0016289) 17006, 1075, 19, 3 2.498 0.266891742676 0.716101740739 19 microfilament motor activity(GO:0000146) 17006, 29, 22, 1 26.655 0.12514191729 0.566602479291 22 ATPase activity, coupled(GO:0042623) 17006, 1809, 362, 44 1.143 0.651620840765 0.898965850169 362 microtubule binding(GO:0008017) 17006, 265, 233, 4 1.102 0.896593352942 0.997573454763 233 SNARE binding(GO:0000149) 17006, 39, 106, 1 4.114 0.58846296232 0.880207012751 106 receptor tyrosine kinase binding(GO:0030971) 17006, 13, 67, 1 19.525 0.212942497435 0.673655340767 67 growth factor binding(GO:0019838) 17006, 1699, 132, 22 1.668 0.0789962089218 0.47023778186 132 BMP binding(GO:0036122) 17006, 1415, 11, 1 1.093 0.639280050346 0.893607972947 11 glucosyltransferase activity(GO:0046527) 17006, 1178, 20, 5 3.609 0.0416738214177 0.354208787353 20 estradiol 17-beta-dehydrogenase activity(GO:0004303) 17006, 328, 11, 1 4.713 0.318661765558 0.741390999598 11 modification-dependent protein binding(GO:0140030) 17006, 1559, 140, 14 1.091 0.811643903543 0.950779632485 140 delayed rectifier potassium channel activity(GO:0005251) 17006, 22, 33, 1 23.424 0.153276801473 0.606647264069 33 insulin-like growth factor binding(GO:0005520) 17006, 1091, 22, 4 2.834 0.151519770908 0.601999705183 22 anion channel activity(GO:0005253) 17006, 119, 89, 1 1.606 0.817272792203 0.954716720116 89 chloride channel activity(GO:0005254) 17006, 1433, 75, 8 1.266 0.654091941326 0.899703029813 75 translation repressor activity(GO:0030371) 17006, 199, 25, 1 3.418 0.483241868491 0.833231956021 25 disordered domain specific binding(GO:0097718) 17006, 304, 30, 5 9.323 0.0011858860759 0.0532617528871 30 glucocorticoid receptor binding(GO:0035259) 17006, 92, 14, 1 13.203 0.182668274258 0.627714423064 14 steroid hormone receptor binding(GO:0035258) 17006, 296, 91, 7 4.419 0.00885648332313 0.186709128016 91 UDP-glucosyltransferase activity(GO:0035251) 17006, 873, 11, 1 1.771 0.538929514215 0.853404342611 11 UDP-galactosyltransferase activity(GO:0035250) 17006, 72, 29, 1 8.145 0.309112123426 0.735062494398 29 nuclear hormone receptor binding(GO:0035257) 17006, 392, 153, 13 3.686 0.000690532582613 0.0464317696171 153 phosphatidylinositol phosphate kinase activity(GO:0016307) 17006, 718, 16, 2 2.961 0.298259012206 0.735062494398 16 ionotropic glutamate receptor binding(GO:0035255) 17006, 1858, 33, 3 0.832 0.865881428481 0.980952531603 33 cytidine deaminase activity(GO:0004126) 17006, 144, 12, 1 9.841 0.204901867285 0.663522347664 12 MHC protein complex binding(GO:0023023) 17006, 781, 19, 3 3.438 0.157776752202 0.610424663013 19 endopeptidase activity(GO:0004175) 17006, 111, 445, 1 0.344 0.999458868927 1.0 445 structural constituent of muscle(GO:0008307) 17006, 402, 44, 11 10.576 5.38839414389e-08 2.78310557532e-05 44 glutathione transferase activity(GO:0004364) 17006, 1528, 28, 3 1.192 0.695151403247 0.913316761564 28 clathrin binding(GO:0030276) 17006, 1889, 57, 8 1.264 0.625018345126 0.891773412314 57 GABA receptor binding(GO:0050811) 17006, 1910, 16, 1 0.556 0.852079296239 0.973999447915 16 antigen binding(GO:0003823) 17006, 182, 58, 1 1.611 0.77600774055 0.940250413334 58 LRR domain binding(GO:0030275) 17006, 553, 17, 4 7.236 0.00883490689762 0.186709128016 17 CXCR chemokine receptor binding(GO:0045236) 17006, 1897, 11, 1 0.815 0.728521671039 0.921739698866 11 phosphatidylinositol-3,5-bisphosphate phosphatase activity(GO:0106018) 17006, 561, 15, 1 2.021 0.545558420862 0.853881589016 15 microtubule plus-end binding(GO:0051010) 17006, 1816, 17, 4 2.203 0.236003265749 0.706922066586 17 nuclear receptor transcription coactivator activity(GO:0030374) 17006, 49, 66, 2 10.517 0.0869916374853 0.485742494715 66 glutamate receptor binding(GO:0035254) 17006, 304, 49, 1 1.142 0.837276294694 0.966048179194 49 cyclosporin A binding(GO:0016018) 17006, 219, 23, 1 3.376 0.482205637979 0.832973953231 23 phosphate ion binding(GO:0042301) 17006, 1837, 12, 2 1.543 0.511271141347 0.844743089721 12 dynein complex binding(GO:0070840) 17006, 805, 22, 2 1.92 0.499834860624 0.844743089721 22 DNA-dependent ATPase activity(GO:0008094) 17006, 1540, 90, 10 1.227 0.672107715422 0.901521222362 90 5S rRNA binding(GO:0008097) 17006, 872, 11, 1 1.773 0.538744365624 0.853404342611 11 collagen binding(GO:0005518) 17006, 1992, 67, 10 1.274 0.597033753612 0.881268858068 67 DNA replication origin binding(GO:0003688) 17006, 1566, 17, 2 1.278 0.623445083864 0.891773412314 17 anion:anion antiporter activity(GO:0015301) 17006, 292, 34, 2 3.426 0.317674561858 0.74076257878 34 cytoskeletal protein binding(GO:0008092) 17006, 434, 942, 58 2.413 1.45500544255e-08 1.50302062215e-05 942 carbon-oxygen lyase activity(GO:0016835) 17006, 1065, 77, 8 1.659 0.370132567494 0.789973021119 77 hydro-lyase activity(GO:0016836) 17006, 1065, 58, 6 1.652 0.433096588696 0.821849554378 58 carbon-carbon lyase activity(GO:0016830) 17006, 54, 53, 1 5.942 0.429152597134 0.821849554378 53 carboxy-lyase activity(GO:0016831) 17006, 54, 34, 1 9.263 0.295762599455 0.735062494398 34 chloride ion binding(GO:0031404) 17006, 119, 13, 1 10.993 0.195060870694 0.645826536626 13 virion binding(GO:0046790) 17006, 302, 11, 1 5.119 0.30472936189 0.735062494398 11 organic hydroxy compound transmembrane transporter activity(GO:1901618) 17006, 163, 43, 2 4.853 0.226044933179 0.688808413229 43 DNA binding, bending(GO:0008301) 17006, 633, 20, 3 4.03 0.117283256405 0.550698199393 20 catalytic activity, acting on a rRNA(GO:0140102) 17006, 1970, 20, 3 1.295 0.615770626632 0.890715387283 20 phosphatidylglycerol binding(GO:1901611) 17006, 571, 14, 3 6.382 0.0376983695654 0.343720048811 14 arachidonic acid epoxygenase activity(GO:0008392) 17006, 1222, 16, 1 0.87 0.752979356674 0.930059447969 16 glutathione peroxidase activity(GO:0004602) 17006, 736, 21, 1 1.1 0.744085531691 0.926072715948 21 MHC class II protein complex binding(GO:0023026) 17006, 781, 16, 3 4.083 0.107086012653 0.525948260298 16 type I transforming growth factor beta receptor binding(GO:0034713) 17006, 1415, 11, 3 3.278 0.134236166379 0.577774832791 11 receptor signaling complex scaffold activity(GO:0030159) 17006, 557, 24, 2 2.544 0.392878418895 0.808417163036 24 TBP-class protein binding(GO:0017025) 17006, 1716, 22, 2 0.901 0.788285056569 0.945540137438 22 myosin binding(GO:0017022) 17006, 102, 67, 4 9.954 0.00563554403416 0.145537924682 67 phosphoric ester hydrolase activity(GO:0042578) 17006, 1902, 375, 47 1.121 0.700162075402 0.913351112695 375 exopeptidase activity(GO:0008238) 17006, 1665, 115, 12 1.066 0.828138499557 0.960120168398 115 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) 17006, 474, 58, 4 2.474 0.278974792722 0.722258047323 58 ATPase regulator activity(GO:0060590) 17006, 43, 44, 2 17.977 0.0327214222633 0.325011819211 44 NAD+ kinase activity(GO:0003951) 17006, 948, 17, 3 3.166 0.172647250211 0.623962323985 17 retinol dehydrogenase activity(GO:0004745) 17006, 1835, 20, 3 1.39 0.570070669158 0.870390149809 20 peptidase activity(GO:0008233) 17006, 218, 649, 5 0.601 0.99930337796 1.0 649 metalloexopeptidase activity(GO:0008235) 17006, 1665, 61, 7 1.172 0.722223645996 0.919617906285 61 cysteine-type peptidase activity(GO:0008234) 17006, 185, 200, 3 1.379 0.809757706634 0.950779632485 200 metallopeptidase activity(GO:0008237) 17006, 1728, 185, 21 1.117 0.768225882128 0.937740091323 185 lipid phosphatase activity(GO:0042577) 17006, 0, 11, 0 0.0 1.0 1.0 11 ubiquitin-like protein transferase activity(GO:0019787) 17006, 358, 431, 15 1.653 0.261399792108 0.711021691352 431 tau protein binding(GO:0048156) 17006, 1107, 45, 6 2.048 0.243574231658 0.711021691352 45 calcium-release channel activity(GO:0015278) 17006, 1892, 21, 5 2.14 0.208075810698 0.669602219475 21 peptide binding(GO:0042277) 17006, 219, 291, 7 1.868 0.402600766478 0.81055633192 291 purinergic receptor activity(GO:0035586) 17006, 1338, 26, 6 2.933 0.0591739107634 0.415757769475 26 outward rectifier potassium channel activity(GO:0015271) 17006, 468, 16, 1 2.271 0.529088847095 0.844743089721 16 chaperone binding(GO:0051087) 17006, 708, 101, 8 1.903 0.263180573676 0.711021691352 101 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) 17006, 468, 15, 4 9.69 0.00275659216853 0.0840591735169 15 unfolded protein binding(GO:0051082) 17006, 747, 124, 10 1.836 0.230794732838 0.6994832517 124 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) 17006, 784, 53, 5 2.046 0.314909155605 0.737644348616 53 AU-rich element binding(GO:0017091) 17006, 690, 28, 2 1.76 0.560897631118 0.864786944694 28 anion:sodium symporter activity(GO:0015373) 17006, 1676, 13, 2 1.561 0.509474700003 0.844743089721 13 solute:sodium symporter activity(GO:0015370) 17006, 1967, 73, 11 1.303 0.557163675879 0.86289366894 73 cation:chloride symporter activity(GO:0015377) 17006, 1776, 16, 2 1.197 0.646331504683 0.898965850169 16 dynein light chain binding(GO:0045503) 17006, 1027, 25, 1 0.662 0.875992195537 0.983180024081 25 actinin binding(GO:0042805) 17006, 43, 39, 3 30.422 0.000996990521368 0.0491496331736 39 double-stranded DNA binding(GO:0003690) 17006, 1997, 950, 138 1.237 0.0534325655445 0.396756095243 950 ATPase activator activity(GO:0001671) 17006, 43, 27, 1 14.648 0.201877870004 0.662031237189 27 histone methyltransferase activity (H3-K4 specific)(GO:0042800) 17006, 1625, 16, 3 1.962 0.357228810199 0.780325126639 16 single-stranded DNA binding(GO:0003697) 17006, 1750, 108, 14 1.26 0.592987261091 0.880207012751 108 identical protein binding(GO:0042802) 17006, 308, 1702, 53 1.719 0.00135635284053 0.0536820152437 1702 protein homodimerization activity(GO:0042803) 17006, 372, 848, 31 1.671 0.0450353036003 0.365498959845 848 narrow pore channel activity(GO:0022842) 17006, 1783, 19, 2 1.004 0.735137904877 0.921739698866 19 chemokine receptor binding(GO:0042379) 17006, 171, 63, 2 3.157 0.401943732109 0.81055633192 63 potassium channel regulator activity(GO:0015459) 17006, 131, 51, 2 5.091 0.221778699108 0.688808413229 51 DNA secondary structure binding(GO:0000217) 17006, 1956, 25, 5 1.739 0.35565500548 0.780325126639 25 four-way junction DNA binding(GO:0000400) 17006, 1956, 16, 3 1.63 0.462995281971 0.821849554378 16 pseudouridine synthase activity(GO:0009982) 17006, 1871, 13, 1 0.699 0.781528648199 0.943129782231 13 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) 17006, 1040, 12, 2 2.725 0.306688161401 0.735062494398 12 voltage-gated anion channel activity(GO:0008308) 17006, 119, 18, 1 7.939 0.271306717255 0.720123263067 18 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) 17006, 1064, 15, 2 2.131 0.416589652442 0.814304198748 15 enhancer binding(GO:0035326) 17006, 1924, 131, 26 1.754 0.024163117932 0.283286111312 131 Toll-like receptor binding(GO:0035325) 17006, 1681, 12, 2 1.686 0.469253978043 0.822109834111 12 serine-type endopeptidase inhibitor activity(GO:0004867) 17006, 336, 95, 1 0.533 0.97738718905 1.0 95 cysteine-type endopeptidase inhibitor activity(GO:0004869) 17006, 1590, 57, 4 0.751 0.942009349902 1.0 57 cGMP binding(GO:0030553) 17006, 24, 16, 1 44.286 0.0749580164533 0.469282612099 16 cAMP binding(GO:0030552) 17006, 24, 23, 2 61.616 0.0026546706625 0.0840591735169 23 DNA-binding transcription repressor activity, RNA polymerase II-specific(GO:0001227) 17006, 357, 220, 15 3.248 0.000920458644755 0.0491496331736 220 neuropeptide hormone activity(GO:0005184) 17006, 18, 27, 1 34.992 0.107429896344 0.525948260298 27 cytoskeletal adaptor activity(GO:0008093) 17006, 339, 13, 2 7.718 0.079198983574 0.47023778186 13 transcription coactivator binding(GO:0001223) 17006, 1986, 22, 3 1.168 0.682615960133 0.904028572842 22 transcription corepressor binding(GO:0001222) 17006, 1479, 15, 1 0.767 0.76730208196 0.937740091323 15 nuclease activity(GO:0004518) 17006, 62, 204, 1 1.345 0.906368595058 1.0 204 catecholamine binding(GO:1901338) 17006, 1195, 20, 2 1.423 0.617378719549 0.890715387283 20 tetrapyrrole binding(GO:0046906) 17006, 159, 140, 1 0.764 0.96133496654 1.0 140 ubiquitin-like protein binding(GO:0032182) 17006, 1971, 99, 15 1.307 0.507741635805 0.844743089721 99 SUMO binding(GO:0032183) 17006, 1702, 16, 1 0.624 0.822118849394 0.95528545717 16 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) 17006, 1222, 32, 1 0.435 0.951604118248 1.0 32 sulfate transmembrane transporter activity(GO:0015116) 17006, 1676, 16, 4 2.537 0.168946819955 0.623962323985 16 phosphatidylinositol binding(GO:0035091) 17006, 1948, 243, 35 1.257 0.410109747263 0.813135065111 243 phosphate ion transmembrane transporter activity(GO:0015114) 17006, 1837, 14, 2 1.322 0.592564633826 0.880207012751 14 nucleoside monophosphate kinase activity(GO:0050145) 17006, 1858, 23, 3 1.194 0.669630770485 0.900688262904 23 gated channel activity(GO:0022836) 17006, 123, 347, 6 2.391 0.249143769296 0.711021691352 347 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653) 17006, 514, 13, 2 5.09 0.148450161795 0.598429452064 13 protein tag(GO:0031386) 17006, 614, 11, 1 2.518 0.462187071543 0.821849554378 11 p53 binding(GO:0002039) 17006, 1265, 65, 12 2.482 0.0182910699859 0.253836931701 65 enzyme activator activity(GO:0008047) 17006, 264, 526, 20 2.449 0.00341565234595 0.0970821278289 526 receptor antagonist activity(GO:0048019) 17006, 1881, 30, 4 1.205 0.673740932879 0.901521222362 30 chemoattractant activity(GO:0042056) 17006, 480, 37, 2 1.915 0.562539430598 0.866025680786 37 extracellular matrix structural constituent(GO:0005201) 17006, 1811, 158, 24 1.426 0.24712971407 0.711021691352 158 histone methyltransferase activity(GO:0042054) 17006, 1755, 58, 13 2.172 0.0337294866793 0.328703393771 58 ubiquitin-like protein ligase binding(GO:0044389) 17006, 226, 305, 10 2.467 0.0673292465107 0.454355180796 305 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) 17006, 0, 12, 0 0.0 1.0 1.0 12 transforming growth factor beta receptor binding(GO:0005160) 17006, 1602, 51, 12 2.498 0.0142293136312 0.228232607772 51 platelet-derived growth factor receptor binding(GO:0005161) 17006, 154, 15, 2 14.724 0.0311296573896 0.320680675622 15 tumor necrosis factor receptor binding(GO:0005164) 17006, 0, 32, 0 0.0 1.0 1.0 32 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) 17006, 1896, 17, 5 2.638 0.106361317421 0.525699717203 17 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662) 17006, 452, 34, 2 2.213 0.489746520424 0.837596284102 34 oxidoreductase activity, acting on NAD(P)H(GO:0016651) 17006, 269, 101, 4 2.504 0.312357460896 0.737644348616 101 Lys48-specific deubiquitinase activity(GO:1990380) 17006, 1179, 15, 1 0.962 0.721388957428 0.919617906285 15 ubiquitin-specific protease binding(GO:1990381) 17006, 991, 15, 4 4.576 0.0350807615513 0.337491157186 15 Rac GTPase binding(GO:0048365) 17006, 200, 69, 2 2.465 0.516772119878 0.844743089721 69 modified amino acid binding(GO:0072341) 17006, 366, 89, 4 2.088 0.416753139321 0.814304198748 89 lipase activator activity(GO:0060229) 17006, 1411, 13, 1 0.927 0.703161502631 0.91426919723 13 growth factor activity(GO:0008083) 17006, 5, 162, 1 20.995 0.247645727864 0.711021691352 162 long-chain fatty acid-CoA ligase activity(GO:0004467) 17006, 0, 13, 0 0.0 1.0 1.0 13 ionotropic glutamate receptor activity(GO:0004970) 17006, 1320, 19, 2 1.356 0.622170087711 0.891403190854 19 ATPase binding(GO:0051117) 17006, 12, 80, 1 17.715 0.236690915828 0.706922066586 80 glucuronosyltransferase activity(GO:0015020) 17006, 1961, 33, 4 1.051 0.76889240789 0.937740091323 33 coreceptor activity(GO:0015026) 17006, 1942, 44, 13 2.587 0.00615393599096 0.155049167772 44 antioxidant activity(GO:0016209) 17006, 1528, 85, 4 0.524 0.993893500398 1.0 85 acetylcholine receptor binding(GO:0033130) 17006, 1072, 13, 1 1.22 0.645408323614 0.898965850169 13 acylglycerol lipase activity(GO:0047372) 17006, 0, 12, 0 0.0 1.0 1.0 12 steroid dehydrogenase activity(GO:0016229) 17006, 1352, 34, 4 1.48 0.551566696517 0.858796628528 34 catalytic activity, acting on RNA(GO:0140098) 17006, 548, 353, 14 1.231 0.730759902129 0.921739698866 353 cyclin binding(GO:0030332) 17006, 1014, 30, 6 3.354 0.0379323190362 0.343720048811 30 estrogen receptor binding(GO:0030331) 17006, 296, 41, 5 7.006 0.00467101544482 0.123722024474 41 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757) 17006, 2000, 157, 31 1.679 0.0224128072486 0.282201599296 157 enzyme regulator activity(GO:0030234) 17006, 273, 1034, 31 1.868 0.00972170395258 0.20085040366 1034 oxidoreductase activity, acting on a heme group of donors(GO:0016675) 17006, 554, 24, 2 2.558 0.390660554986 0.807104706601 24 catalytic activity, acting on DNA(GO:0140097) 17006, 98, 187, 2 1.856 0.732859748966 0.921739698866 187 acid-thiol ligase activity(GO:0016878) 17006, 699, 30, 1 0.811 0.86083425743 0.978263793097 30 ligase activity, forming carbon-nitrogen bonds(GO:0016879) 17006, 126, 50, 1 2.699 0.626116301875 0.891943663175 50 actin monomer binding(GO:0003785) 17006, 84, 28, 2 14.461 0.0403898781399 0.354208787353 28 phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595) 17006, 1213, 13, 2 2.157 0.387086207573 0.803308358374 13 catalytic activity, acting on a tRNA(GO:0140101) 17006, 2000, 122, 19 1.324 0.439206381418 0.821849554378 122 metalloendopeptidase inhibitor activity(GO:0008191) 17006, 1754, 15, 3 1.939 0.358375238051 0.780325126639 15 ligase activity(GO:0016874) 17006, 1698, 154, 18 1.171 0.697586568126 0.913316761564 154 apolipoprotein binding(GO:0034185) 17006, 1912, 16, 1 0.556 0.852367377459 0.973999447915 16 electron transfer activity(GO:0009055) 17006, 46, 106, 1 3.488 0.634857934429 0.891943663175 106 protein phosphatase 2A binding(GO:0051721) 17006, 1321, 31, 7 2.907 0.0415675157782 0.354208787353 31 neuropilin binding(GO:0038191) 17006, 1595, 19, 5 2.806 0.0922365000737 0.489576697981 19 steroid hydroxylase activity(GO:0008395) 17006, 1222, 35, 2 0.795 0.876581609079 0.983180024081 35 thyroid hormone receptor binding(GO:0046966) 17006, 511, 29, 3 3.443 0.181656193947 0.627631006816 29 translation regulator activity(GO:0045182) 17006, 659, 142, 8 1.454 0.568344975642 0.870025218778 142 molecular carrier activity(GO:0140104) 17006, 159, 40, 2 5.348 0.193855778081 0.643900381858 40 isoprenoid binding(GO:0019840) 17006, 163, 43, 1 2.426 0.638212604294 0.893324688666 43 retinoid X receptor binding(GO:0046965) 17006, 318, 16, 2 6.685 0.108656579231 0.529444558232 16 vitamin binding(GO:0019842) 17006, 771, 135, 7 1.144 0.813369120113 0.951540544821 135 amino acid transmembrane transporter activity(GO:0015171) 17006, 1419, 74, 9 1.458 0.470778857729 0.822867275861 74 fatty acid ligase activity(GO:0015645) 17006, 0, 21, 0 0.0 1.0 1.0 21 transmembrane signaling receptor activity(GO:0004888) 17006, 32, 1248, 2 0.852 0.989866247776 1.0 1248 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) 17006, 1663, 28, 5 1.826 0.330072765288 0.749623312777 28 peptidase activator activity(GO:0016504) 17006, 1974, 39, 7 1.546 0.408182008684 0.812324557007 39 peptidase activator activity involved in apoptotic process(GO:0016505) 17006, 202, 20, 1 4.209 0.415358258108 0.814304198748 20 protein-hormone receptor activity(GO:0016500) 17006, 923, 19, 3 2.909 0.210190493505 0.670144382069 19 methylated histone binding(GO:0035064) 17006, 920, 63, 4 1.174 0.77237087262 0.939763382117 63 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters(GO:0016894) 17006, 1956, 22, 3 1.186 0.672934340528 0.901521222362 22 dynein heavy chain binding(GO:0045504) 17006, 0, 14, 0 0.0 1.0 1.0 14 NAD binding(GO:0051287) 17006, 7, 58, 1 41.887 0.116294594938 0.548549390736 58 phospholipid-translocating ATPase activity(GO:0004012) 17006, 85, 23, 1 8.699 0.276352286384 0.720466987857 23 androgen receptor binding(GO:0050681) 17006, 1677, 44, 10 2.305 0.0497841143118 0.38378350809 44 oxygen carrier activity(GO:0005344) 17006, 159, 13, 1 8.227 0.236907455025 0.706922066586 13 2-oxoglutarate-dependent dioxygenase activity(GO:0016706) 17006, 1933, 47, 5 0.936 0.858531639974 0.977282103233 47 GABA receptor activity(GO:0016917) 17006, 626, 22, 1 1.235 0.726396034787 0.921739698866 22 neuropeptide receptor binding(GO:0071855) 17006, 18, 29, 1 32.579 0.114851600595 0.548549390736 29 protein methyltransferase activity(GO:0008276) 17006, 1976, 90, 20 1.913 0.0219421927787 0.279830680746 90 secondary active sulfate transmembrane transporter activity(GO:0008271) 17006, 1676, 13, 3 2.342 0.258407328229 0.711021691352 13 fatty-acyl-CoA binding(GO:0000062) 17006, 1075, 21, 2 1.507 0.591217942068 0.880207012751 21 protein phosphorylated amino acid binding(GO:0045309) 17006, 13, 49, 1 26.697 0.155643500275 0.610424663013 49 O-acyltransferase activity(GO:0008374) 17006, 1598, 50, 9 1.916 0.169820739456 0.623962323985 50 acetylglucosaminyltransferase activity(GO:0008375) 17006, 83, 54, 2 7.589 0.131887644365 0.574852053288 54 acetylgalactosaminyltransferase activity(GO:0008376) 17006, 72, 45, 1 5.249 0.442456049688 0.821849554378 45 proton transmembrane transporter activity(GO:0015078) 17006, 124, 129, 2 2.126 0.642011768727 0.896213725804 129 retinal binding(GO:0016918) 17006, 163, 16, 1 6.521 0.295942528718 0.735062494398 16 pre-mRNA binding(GO:0036002) 17006, 1972, 34, 5 1.268 0.633330360311 0.891943663175 34 ATP-dependent helicase activity(GO:0008026) 17006, 813, 76, 6 1.651 0.460101936795 0.821849554378 76 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) 17006, 61, 49, 1 5.69 0.429736727534 0.821849554378 49 protein phosphatase activator activity(GO:0072542) 17006, 6, 13, 1 218.026 0.0184295932987 0.253836931701 13 tropomyosin binding(GO:0005523) 17006, 21, 15, 2 107.975 0.000792268768412 0.0481419786923 15 G-protein alpha-subunit binding(GO:0001965) 17006, 1752, 22, 3 1.324 0.606025257956 0.885587488671 22 transcription corepressor activity(GO:0003714) 17006, 344, 244, 9 1.823 0.317535523558 0.74076257878 244 transcription coactivator activity(GO:0003713) 17006, 1019, 317, 33 1.737 0.0164890560106 0.236572150819 317 transcription coregulator activity(GO:0003712) 17006, 344, 562, 22 1.935 0.0301124176685 0.314203307592 562 drug transmembrane transporter activity(GO:0015238) 17006, 1319, 100, 12 1.547 0.336790728792 0.756314832265 100 poly(A) binding(GO:0008143) 17006, 1546, 23, 6 2.87 0.0599689328671 0.415757769475 23 PDZ domain binding(GO:0030165) 17006, 505, 86, 5 1.958 0.387267727464 0.803308358374 86 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) 17006, 372, 28, 1 1.633 0.692194291268 0.91320140853 28 magnesium ion transmembrane transporter activity(GO:0015095) 17006, 0, 17, 0 0.0 1.0 1.0 17 regulatory RNA binding(GO:0061980) 17006, 1788, 38, 3 0.751 0.90685030204 1.0 38 protein ADP-ribosylase activity(GO:1990404) 17006, 296, 16, 1 3.591 0.423402046301 0.815996854158 16 carbonate dehydratase activity(GO:0004089) 17006, 928, 16, 1 1.145 0.710631417383 0.917602817696 16 deoxyribonuclease activity(GO:0004536) 17006, 62, 60, 1 4.572 0.504896311678 0.844743089721 60 translation factor activity, RNA binding(GO:0008135) 17006, 785, 88, 8 1.969 0.225472446719 0.688808413229 88 sterol binding(GO:0032934) 17006, 1974, 55, 11 1.723 0.198061172562 0.653665147786 55 hormone activity(GO:0005179) 17006, 37, 121, 3 11.396 0.0190623077081 0.25825372595 121 inorganic anion transmembrane transporter activity(GO:0015103) 17006, 250, 158, 4 1.722 0.604715107766 0.885587488671 158 protein kinase activity(GO:0004672) 17006, 141, 654, 14 2.582 0.0150157857637 0.228232607772 654 translation regulator activity, nucleic acid binding(GO:0090079) 17006, 659, 111, 8 1.86 0.289656363464 0.735062494398 111 ubiquitin-like protein conjugating enzyme activity(GO:0061650) 17006, 209, 41, 3 5.954 0.0677354286957 0.454355180796 41 steroid binding(GO:0005496) 17006, 1974, 94, 18 1.65 0.121624894216 0.56591010313 94 snoRNA binding(GO:0030515) 17006, 1152, 24, 3 1.845 0.436284391978 0.821849554378 24 drug binding(GO:0008144) 17006, 966, 1722, 123 1.257 0.0558856472685 0.400901900197 1722 transcription cofactor binding(GO:0001221) 17006, 1986, 41, 5 1.044 0.789018004329 0.945540137438 41 low-density lipoprotein particle binding(GO:0030169) 17006, 1681, 15, 1 0.674 0.798216919144 0.948858547153 15 dipeptidyl-peptidase activity(GO:0008239) 17006, 560, 14, 1 2.169 0.519048190255 0.844743089721 14 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) 17006, 1771, 26, 4 1.477 0.519226420919 0.844743089721 26 oxidoreductase activity, acting on CH-OH group of donors(GO:0016614) 17006, 7, 132, 1 18.405 0.259254948924 0.711021691352 132 dioxygenase activity(GO:0051213) 17006, 1578, 92, 11 1.289 0.595656858533 0.881268858068 92 neurotransmitter receptor regulator activity(GO:0099602) 17006, 0, 14, 0 0.0 1.0 1.0 14 cyclase activity(GO:0009975) 17006, 231, 23, 3 9.602 0.0180224057673 0.253836931701 23 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen(GO:0016705) 17006, 16, 164, 1 6.481 0.505872520247 0.844743089721 164 phosphoprotein binding(GO:0051219) 17006, 13, 81, 1 16.15 0.252891616762 0.711021691352 81 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) 17006, 13, 12, 1 109.013 0.0333916903095 0.328510629426 12 telomerase RNA binding(GO:0070034) 17006, 1236, 22, 5 3.127 0.071194303055 0.459924790908 22 snRNA binding(GO:0017069) 17006, 1152, 39, 6 2.271 0.170735229757 0.623962323985 39 nucleosomal DNA binding(GO:0031492) 17006, 1991, 44, 6 1.165 0.709997643502 0.917602817696 44 acetylcholine-gated cation-selective channel activity(GO:0022848) 17006, 0, 16, 0 0.0 1.0 1.0 16 catalytic activity, acting on a glycoprotein(GO:0140103) 17006, 1308, 22, 3 1.773 0.454020722022 0.821849554378 22 sterol transporter activity(GO:0015248) 17006, 1955, 35, 5 1.243 0.651316819176 0.898965850169 35 3'-5' DNA helicase activity(GO:0043138) 17006, 780, 15, 2 2.907 0.295794411199 0.735062494398 15 Rho guanyl-nucleotide exchange factor activity(GO:0005089) 17006, 460, 80, 6 2.773 0.115564161054 0.548549390736 80 Ras guanyl-nucleotide exchange factor activity(GO:0005088) 17006, 1554, 257, 40 1.703 0.00707696832849 0.16614791553 257 cytokine activity(GO:0005125) 17006, 5, 219, 1 15.531 0.320439441847 0.741707155508 219 death receptor binding(GO:0005123) 17006, 1064, 17, 1 0.94 0.754535448832 0.930059447969 17 spectrin binding(GO:0030507) 17006, 1917, 28, 4 1.267 0.6347781388 0.891943663175 28 protein kinase C binding(GO:0005080) 17006, 1041, 49, 8 2.667 0.052275274406 0.391306945372 49 guanyl-nucleotide exchange factor activity(GO:0005085) 17006, 521, 331, 21 2.071 0.0163455423507 0.236572150819 331 ubiquitin-ubiquitin ligase activity(GO:0034450) 17006, 1394, 13, 1 0.938 0.700265325512 0.913351112695 13 acetylcholine receptor activity(GO:0015464) 17006, 0, 23, 0 0.0 1.0 1.0 23 ARF guanyl-nucleotide exchange factor activity(GO:0005086) 17006, 1255, 19, 1 0.713 0.819780959093 0.954716720116 19 beta-tubulin binding(GO:0048487) 17006, 252, 37, 1 1.824 0.69942879572 0.913351112695 37 organic cation transmembrane transporter activity(GO:0015101) 17006, 1319, 27, 3 1.433 0.592944216265 0.880207012751 27 protein-containing complex scaffold activity(GO:0032947) 17006, 270, 91, 5 3.461 0.0889070339258 0.487291421467 91 NAD+ ADP-ribosyltransferase activity(GO:0003950) 17006, 567, 27, 2 2.222 0.463087868552 0.821849554378 27 bHLH transcription factor binding(GO:0043425) 17006, 52, 28, 1 11.68 0.239100932222 0.707711355259 28 sodium channel activity(GO:0005272) 17006, 1926, 41, 6 1.292 0.612229725885 0.890715387283 41 translation initiation factor binding(GO:0031369) 17006, 521, 31, 1 1.053 0.805384725605 0.950779632485 31 lipase inhibitor activity(GO:0055102) 17006, 302, 18, 1 3.128 0.465972447205 0.822090582663 18 NADP binding(GO:0050661) 17006, 1887, 51, 11 1.944 0.105685998061 0.524873249984 51 protein kinase B binding(GO:0043422) 17006, 592, 12, 2 4.788 0.150596582518 0.601999705183 12 3'-5' exonuclease activity(GO:0008408) 17006, 270, 55, 2 2.29 0.525316377748 0.844743089721 55 5'-3' exonuclease activity(GO:0008409) 17006, 188, 17, 2 10.642 0.0540488150466 0.396756095243 17 adrenergic receptor activity(GO:0004935) 17006, 1195, 17, 2 1.674 0.527751563245 0.844743089721 17 ribonuclease activity(GO:0004540) 17006, 548, 113, 5 1.373 0.697077681373 0.913316761564 113 CARD domain binding(GO:0050700) 17006, 1017, 15, 1 1.115 0.696595870182 0.913316761564 15 NADH dehydrogenase activity(GO:0003954) 17006, 784, 40, 3 1.627 0.567787859515 0.870025218778 40 phosphatidylinositol bisphosphate binding(GO:1902936) 17006, 468, 105, 6 2.076 0.295561403083 0.735062494398 105 complement binding(GO:0001848) 17006, 1563, 20, 2 1.088 0.708302651395 0.916888018661 20 deaminase activity(GO:0019239) 17006, 436, 32, 3 3.657 0.167322302893 0.623962323985 32 ubiquitin binding(GO:0043130) 17006, 1971, 80, 13 1.402 0.419386828027 0.814304198748 80 sequence-specific single stranded DNA binding(GO:0098847) 17006, 1209, 15, 1 0.938 0.725980269882 0.921739698866 15 H4 histone acetyltransferase activity(GO:0010485) 17006, 0, 21, 0 0.0 1.0 1.0 21 carbohydrate:cation symporter activity(GO:0005402) 17006, 354, 19, 1 2.528 0.52780636966 0.844743089721 19 MAP kinase phosphatase activity(GO:0033549) 17006, 145, 15, 1 7.819 0.258136831878 0.711021691352 15 passive transmembrane transporter activity(GO:0022803) 17006, 123, 461, 6 1.799 0.522260722149 0.844743089721 461 oxidoreductase activity, acting on peroxide as acceptor(GO:0016684) 17006, 736, 55, 2 0.84 0.900761559076 0.999194392223 55 chemokine activity(GO:0008009) 17006, 1870, 48, 1 0.189 0.996537588621 1.0 48 transferase activity, transferring nitrogenous groups(GO:0016769) 17006, 669, 23, 2 2.21 0.444184105765 0.821849554378 23 active transmembrane transporter activity(GO:0022804) 17006, 360, 361, 10 1.309 0.715202402293 0.918461791404 361 opsonin binding(GO:0001846) 17006, 1563, 15, 2 1.451 0.555143585635 0.862350863099 15 adenyl nucleotide binding(GO:0030554) 17006, 1047, 1541, 125 1.318 0.0123242646638 0.227338667817 1541 sphingolipid transporter activity(GO:0046624) 17006, 733, 13, 1 1.785 0.57154757579 0.870809212082 13 extracellular ligand-gated ion channel activity(GO:0005230) 17006, 653, 75, 2 0.694 0.954725598087 1.0 75 excitatory extracellular ligand-gated ion channel activity(GO:0005231) 17006, 653, 31, 1 0.84 0.856702396382 0.976792025896 31 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) 17006, 626, 16, 1 1.698 0.599062165079 0.882783475788 16 actin-dependent ATPase activity(GO:0030898) 17006, 1785, 12, 5 3.97 0.0203371556133 0.269336945494 12 sphingolipid binding(GO:0046625) 17006, 947, 22, 3 2.449 0.292766178979 0.735062494398 22 heparan sulfate proteoglycan binding(GO:0043395) 17006, 1249, 15, 1 0.908 0.732102019819 0.921739698866 15 protein phosphatase 1 binding(GO:0008157) 17006, 90, 20, 2 18.896 0.0232610044819 0.282689619174 20 extracellular matrix structural constituent conferring compression resistance(GO:0030021) 17006, 1946, 22, 4 1.589 0.456846511646 0.821849554378 22 phosphatidylinositol phosphate binding(GO:1901981) 17006, 41, 155, 2 5.352 0.270422882001 0.719966075019 155 ubiquitin-like protein-specific protease activity(GO:0019783) 17006, 185, 132, 3 2.089 0.541812545573 0.853404342611 132 myosin V binding(GO:0031489) 17006, 1020, 17, 1 0.981 0.748593843619 0.929029864269 17 death receptor activity(GO:0005035) 17006, 104, 11, 1 14.865 0.148363136923 0.598429452064 11 mannosyltransferase activity(GO:0000030) 17006, 1822, 28, 3 1.0 0.777068337092 0.940250413334 28 calmodulin-dependent protein kinase activity(GO:0004683) 17006, 11, 28, 2 110.429 0.000983462245941 0.0491496331736 28 phosphatidylinositol kinase activity(GO:0052742) 17006, 13, 54, 1 24.225 0.172107140037 0.623962323985 54 MAP kinase kinase kinase activity(GO:0004709) 17006, 428, 27, 2 2.943 0.349168990942 0.775680790631 27 protein tyrosine phosphatase activity(GO:0004725) 17006, 1990, 102, 16 1.341 0.452069629138 0.821849554378 102 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) 17006, 1306, 17, 1 0.766 0.7872142775 0.945540137438 17 ion transmembrane transporter activity(GO:0015075) 17006, 400, 888, 25 1.197 0.727268852912 0.921739698866 888 phosphoprotein phosphatase activity(GO:0004721) 17006, 1896, 185, 24 1.164 0.675449614023 0.902638358713 185 inositol phosphate phosphatase activity(GO:0052745) 17006, 1774, 19, 3 1.514 0.51528102319 0.844743089721 19 DNA-directed DNA polymerase activity(GO:0003887) 17006, 1056, 25, 1 0.644 0.882185055705 0.984442898321 25 voltage-gated potassium channel activity(GO:0005249) 17006, 65, 88, 2 5.946 0.207149373734 0.668704072084 88 carbohydrate derivative transmembrane transporter activity(GO:1901505) 17006, 848, 45, 4 1.783 0.458365295447 0.821849554378 45 voltage-gated chloride channel activity(GO:0005247) 17006, 119, 12, 1 11.909 0.179042139136 0.627201030964 12 calcium channel regulator activity(GO:0005246) 17006, 1541, 49, 10 2.252 0.0596474579073 0.415757769475 49 voltage-gated calcium channel activity(GO:0005245) 17006, 302, 48, 3 3.519 0.203969299129 0.662579515723 48 voltage-gated ion channel activity(GO:0005244) 17006, 303, 200, 9 2.526 0.0727383030426 0.466699795298 200 gap junction channel activity(GO:0005243) 17006, 266, 14, 1 4.567 0.358939180431 0.780325126639 14 inward rectifier potassium channel activity(GO:0005242) 17006, 65, 21, 2 24.917 0.0144074773114 0.228232607772 21 mannose binding(GO:0005537) 17006, 1268, 22, 1 0.61 0.867948319346 0.980952531603 22 glucose binding(GO:0005536) 17006, 982, 11, 2 3.149 0.255600822162 0.711021691352 11 cytokine receptor binding(GO:0005126) 17006, 13, 281, 2 9.311 0.143106453986 0.591315867871 281 nucleobase-containing compound transmembrane transporter activity(GO:0015932) 17006, 848, 43, 5 2.332 0.220285599041 0.688808413229 43 calcium ion transmembrane transporter activity(GO:0015085) 17006, 370, 139, 6 1.984 0.351650155402 0.777017999018 139 histone-lysine N-methyltransferase activity(GO:0018024) 17006, 1755, 45, 12 2.584 0.0100060048388 0.20267064703 45 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) 17006, 1203, 15, 2 1.885 0.459771464097 0.821849554378 15 glycolipid binding(GO:0051861) 17006, 947, 21, 2 1.71 0.535396256745 0.852155777594 21 cyclic-nucleotide phosphodiesterase activity(GO:0004112) 17006, 1204, 29, 3 1.461 0.587781284375 0.880207012751 29 Lys63-specific deubiquitinase activity(GO:0061578) 17006, 0, 12, 0 0.0 1.0 1.0 12 monosaccharide binding(GO:0048029) 17006, 1415, 75, 10 1.602 0.330182582104 0.749623312777 75 G protein-coupled receptor binding(GO:0001664) 17006, 51, 271, 3 3.691 0.278342833724 0.722258047323 271 mRNA 5'-UTR binding(GO:0048027) 17006, 1438, 25, 3 1.419 0.591851544016 0.880207012751 25 CCR chemokine receptor binding(GO:0048020) 17006, 171, 41, 2 4.851 0.221036860905 0.688808413229 41 long-chain fatty acid binding(GO:0036041) 17006, 1576, 14, 3 2.312 0.269272831172 0.719024168564 14 L-ascorbic acid binding(GO:0031418) 17006, 1178, 20, 4 2.887 0.138715721675 0.582865053113 20 ATP-dependent microtubule motor activity(GO:1990939) 17006, 1771, 44, 5 1.091 0.763931077381 0.936110086518 44 amide transmembrane transporter activity(GO:0042887) 17006, 68, 48, 2 10.42 0.0792075256957 0.47023778186 48 calcium-dependent phospholipase A2 activity(GO:0047498) 17006, 1013, 16, 1 1.049 0.722874869219 0.919617906285 16 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) 17006, 124, 16, 1 8.572 0.254978490679 0.711021691352 16 lyase activity(GO:0016829) 17006, 59, 188, 2 3.066 0.505247996607 0.844743089721 188 neuropeptide binding(GO:0042923) 17006, 32, 24, 1 22.143 0.145680964685 0.598429452064 24 divalent inorganic cation transmembrane transporter activity(GO:0072509) 17006, 1686, 25, 7 2.824 0.0411095956362 0.354208787353 25 transmembrane receptor protein kinase activity(GO:0019199) 17006, 1369, 82, 13 1.969 0.0804220304391 0.47471975682 82 general transcription initiation factor binding(GO:0140296) 17006, 52, 42, 1 7.787 0.347258490932 0.773802718543 42 DNA-binding transcription factor binding(GO:0140297) 17006, 338, 339, 20 2.968 0.000279301922348 0.0263580666848 339 potassium ion leak channel activity(GO:0022841) 17006, 1783, 16, 2 1.192 0.64825725039 0.898965850169 16 3'-5'-exoribonuclease activity(GO:0000175) 17006, 270, 32, 1 1.968 0.65725083615 0.900451079235 32 molecular adaptor activity(GO:0060090) 17006, 1298, 210, 29 1.809 0.0140557703515 0.228232607772 210 retinol binding(GO:0019841) 17006, 163, 15, 1 6.955 0.276888087298 0.720466987857 15 mechanosensitive ion channel activity(GO:0008381) 17006, 1011, 15, 1 1.121 0.695677607691 0.913316761564 15 vitamin D receptor binding(GO:0042809) 17006, 274, 15, 1 4.138 0.384832232174 0.802327320665 15 solute:proton symporter activity(GO:0015295) 17006, 1766, 26, 3 1.111 0.717908569954 0.918461791404 26 solute:cation symporter activity(GO:0015294) 17006, 1967, 105, 15 1.235 0.606108765238 0.885587488671 105 antiporter activity(GO:0015297) 17006, 360, 87, 5 2.715 0.181666670898 0.627631006816 87 anion:cation symporter activity(GO:0015296) 17006, 1776, 19, 3 1.512 0.51594360143 0.844743089721 19 secondary active transmembrane transporter activity(GO:0015291) 17006, 360, 235, 8 1.608 0.49610243564 0.842884565816 235 N-acyltransferase activity(GO:0016410) 17006, 50, 109, 1 3.12 0.66697325491 0.900688262904 109 symporter activity(GO:0015293) 17006, 1837, 144, 16 1.029 0.867857363641 0.980952531603 144 solute:proton antiporter activity(GO:0015299) 17006, 119, 22, 1 6.496 0.324948802567 0.745916947999 22 solute:cation antiporter activity(GO:0015298) 17006, 360, 34, 2 2.779 0.394128763088 0.808417163036 34 carboxylic ester hydrolase activity(GO:0052689) 17006, 1075, 141, 17 1.907 0.0548954920289 0.399345375111 141 nucleotidase activity(GO:0008252) 17006, 1391, 16, 1 0.764 0.777322219736 0.940250413334 16 RNA polymerase II activating transcription factor binding(GO:0001102) 17006, 770, 41, 6 3.232 0.0519105420436 0.391306945372 41 RNA polymerase II repressing transcription factor binding(GO:0001103) 17006, 92, 35, 2 10.563 0.0712371408957 0.459924790908 35 nuclear receptor binding(GO:0016922) 17006, 392, 108, 12 4.82 9.44085174866e-05 0.0121904998205 108 heparin binding(GO:0008201) 17006, 423, 156, 4 1.031 0.900512451954 0.999194392223 156 sequence-specific mRNA binding(GO:1990825) 17006, 1778, 11, 2 1.739 0.450943859487 0.821849554378 11 G protein-coupled chemoattractant receptor activity(GO:0001637) 17006, 1818, 26, 5 1.799 0.331642242814 0.751286045673 26 G protein-coupled receptor activity(GO:0004930) 17006, 32, 840, 2 1.265 0.936993296945 1.0 840 ubiquitin-like protein ligase activity(GO:0061659) 17006, 1689, 225, 26 1.163 0.678881879573 0.903717759793 225 alcohol binding(GO:0043178) 17006, 1974, 84, 17 1.744 0.0915431956247 0.489576697981 84 organic acid binding(GO:0043177) 17006, 1200, 215, 18 1.186 0.704509468533 0.91426919723 215 semaphorin receptor activity(GO:0017154) 17006, 129, 11, 1 11.984 0.173996603908 0.623962323985 11 RNA polymerase core enzyme binding(GO:0043175) 17006, 76, 44, 1 5.086 0.446684730083 0.821849554378 44 gamma-catenin binding(GO:0045295) 17006, 0, 11, 0 0.0 1.0 1.0 11 cadherin binding(GO:0045296) 17006, 1987, 316, 58 1.571 0.00409176632071 0.111231437087 316 NAD-dependent protein deacetylase activity(GO:0034979) 17006, 567, 17, 2 3.529 0.251885520134 0.711021691352 17 single-stranded RNA binding(GO:0003727) 17006, 1604, 86, 12 1.479 0.378463159806 0.796237156985 86 RNA helicase activity(GO:0003724) 17006, 528, 48, 2 1.342 0.738746324115 0.921739698866 48 double-stranded RNA binding(GO:0003725) 17006, 1885, 75, 12 1.443 0.396095939948 0.808417163036 75 RNA binding(GO:0003723) 17006, 1764, 1619, 202 1.203 0.0352846514773 0.337491157186 1619 rRNA binding(GO:0019843) 17006, 450, 61, 2 1.239 0.793546621753 0.948589072277 61 Wnt-protein binding(GO:0017147) 17006, 1240, 37, 7 2.595 0.0745840291657 0.469282612099 37 calcium:cation antiporter activity(GO:0015368) 17006, 360, 11, 1 4.294 0.335567163986 0.756314832265 11 inositol 1,4,5 trisphosphate binding(GO:0070679) 17006, 1892, 13, 2 1.383 0.568506314303 0.870025218778 13 damaged DNA binding(GO:0003684) 17006, 1825, 68, 10 1.37 0.506714369114 0.844743089721 68 mRNA binding(GO:0003729) 17006, 1778, 240, 30 1.196 0.590185363974 0.880207012751 240 carbohydrate kinase activity(GO:0019200) 17006, 982, 21, 4 3.299 0.105032567704 0.5241480311 21 protein membrane anchor(GO:0043495) 17006, 542, 14, 2 4.482 0.17972072136 0.627201030964 14 nucleoside kinase activity(GO:0019206) 17006, 217, 13, 1 6.028 0.294412922186 0.735062494398 13 kinase regulator activity(GO:0019207) 17006, 13, 206, 2 12.701 0.0777160438021 0.47023778186 206 nucleobase-containing compound kinase activity(GO:0019205) 17006, 1858, 44, 6 1.248 0.648429916322 0.898965850169 44 phosphatase regulator activity(GO:0019208) 17006, 1461, 94, 20 2.477 0.00125341306638 0.0536820152437 94 kinase activator activity(GO:0019209) 17006, 264, 86, 4 2.996 0.208818310035 0.669904702691 86 RNA 7-methylguanosine cap binding(GO:0000340) 17006, 279, 12, 1 5.079 0.32119666821 0.741707155508 12 alpha-actinin binding(GO:0051393) 17006, 355, 31, 5 7.726 0.00266278567888 0.0840591735169 31 ferrous iron binding(GO:0008198) 17006, 1578, 23, 4 1.874 0.352884095824 0.777247912551 23 mannosidase activity(GO:0015923) 17006, 1947, 15, 1 0.582 0.838926556228 0.966048179194 15 protein serine/threonine phosphatase activity(GO:0004722) 17006, 1633, 77, 8 1.082 0.801677548956 0.950779632485 77 glycosaminoglycan binding(GO:0005539) 17006, 423, 216, 4 0.745 0.982814287685 1.0 216 DNA-binding transcription activator activity(GO:0001216) 17006, 1472, 382, 49 1.482 0.0371839484953 0.343720048811 382 coenzyme binding(GO:0050662) 17006, 325, 289, 13 2.354 0.0374316251906 0.343720048811 289 oxidoreductase activity, oxidizing metal ions(GO:0016722) 17006, 488, 18, 3 5.808 0.0541554786343 0.396756095243 18 flavin adenine dinucleotide binding(GO:0050660) 17006, 325, 79, 6 3.974 0.0268329339185 0.291772849872 79 MHC class I protein binding(GO:0042288) 17006, 764, 19, 1 1.172 0.717202861548 0.918461791404 19 extracellular matrix structural constituent conferring tensile strength(GO:0030020) 17006, 295, 37, 2 3.116 0.362422454306 0.782174437659 37 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664) 17006, 16, 17, 1 62.522 0.0576663563687 0.408361892912 17 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) 17006, 1815, 16, 3 1.757 0.416906076228 0.814304198748 16 phosphatidylcholine transporter activity(GO:0008525) 17006, 1067, 11, 1 1.449 0.574848340801 0.872718905496 11 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) 17006, 53, 17, 1 18.875 0.146583472327 0.598429452064 17 taste receptor activity(GO:0008527) 17006, 30, 30, 1 18.896 0.175778452157 0.623962323985 30 structural molecule activity(GO:0005198) 17006, 307, 796, 24 1.67 0.0993606693564 0.50734985939 796 bicarbonate transmembrane transporter activity(GO:0015106) 17006, 1967, 20, 3 1.297 0.614786326435 0.890715387283 20 R-SMAD binding(GO:0070412) 17006, 296, 23, 4 9.992 0.00335603240038 0.0970821278289 23 voltage-gated cation channel activity(GO:0022843) 17006, 302, 143, 6 2.363 0.224695649009 0.688808413229 143 co-SMAD binding(GO:0070410) 17006, 1602, 12, 2 1.769 0.448281662518 0.821849554378 12 I-SMAD binding(GO:0070411) 17006, 187, 11, 1 8.267 0.230903958209 0.6994832517 11 ubiquitin-protein transferase regulator activity(GO:0055106) 17006, 74, 17, 1 13.518 0.1842513457 0.630237218901 17 protein tyrosine kinase binding(GO:1990782) 17006, 13, 84, 1 15.573 0.26254931107 0.711021691352 84 chloride transmembrane transporter activity(GO:0015108) 17006, 1875, 100, 12 1.088 0.796877345279 0.948589072277 100 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) 17006, 1204, 20, 2 1.412 0.621287075111 0.891403190854 20 beta-1,3-galactosyltransferase activity(GO:0048531) 17006, 72, 16, 1 14.762 0.169962532174 0.623962323985 16 dynactin binding(GO:0034452) 17006, 0, 12, 0 0.0 1.0 1.0 12 integrin binding(GO:0005178) 17006, 1992, 121, 22 1.552 0.139932752345 0.582865053113 121 tubulin binding(GO:0015631) 17006, 434, 316, 9 1.116 0.869496494306 0.981628282643 316 cation transmembrane transporter activity(GO:0008324) 17006, 555, 646, 26 1.233 0.632869531717 0.891943663175 646 caspase binding(GO:0089720) 17006, 1017, 11, 1 1.52 0.565590911268 0.869427695447 11 Rab GTPase binding(GO:0017137) 17006, 1133, 187, 19 1.525 0.243803050584 0.711021691352 187 lipoprotein particle receptor binding(GO:0070325) 17006, 1889, 26, 6 2.078 0.189461219771 0.637280604303 26 3'-5' RNA helicase activity(GO:0034458) 17006, 1567, 19, 1 0.571 0.856439452539 0.976792025896 19 vascular endothelial growth factor receptor binding(GO:0005172) 17006, 154, 13, 1 8.495 0.231745465441 0.699979724562 13 DNA N-glycosylase activity(GO:0019104) 17006, 1390, 14, 2 1.748 0.471632993753 0.822967707005 14 RNA stem-loop binding(GO:0035613) 17006, 906, 17, 2 2.208 0.407116115066 0.812324557007 17 phosphatidylcholine binding(GO:0031210) 17006, 1411, 27, 4 1.786 0.403316509784 0.81055633192 27 hexosaminidase activity(GO:0015929) 17006, 356, 15, 1 3.185 0.448218340253 0.821849554378 15 phosphatidylinositol-4-phosphate binding(GO:0070273) 17006, 1828, 28, 5 1.661 0.396921006271 0.808417163036 28 proteasome binding(GO:0070628) 17006, 757, 16, 1 1.404 0.653370403804 0.899703029813 16 palmitoyltransferase activity(GO:0016409) 17006, 722, 39, 4 2.416 0.263621788759 0.711021691352 39 diacylglycerol kinase activity(GO:0004143) 17006, 158, 11, 1 9.785 0.202907678063 0.662579515723 11 triglyceride lipase activity(GO:0004806) 17006, 973, 26, 2 1.344 0.664454124611 0.900688262904 26 N-acetyltransferase activity(GO:0008080) 17006, 50, 89, 1 3.822 0.593053321273 0.880207012751 89 growth factor receptor binding(GO:0070851) 17006, 180, 134, 3 2.115 0.536206442823 0.852155777594 134 amino acid:sodium symporter activity(GO:0005283) 17006, 1419, 15, 4 3.196 0.0951436589798 0.496380806698 15 sulfur compound transmembrane transporter activity(GO:1901682) 17006, 1695, 35, 7 2.007 0.189147389151 0.637280604303 35 transition metal ion transmembrane transporter activity(GO:0046915) 17006, 1738, 39, 8 2.007 0.157634559345 0.610424663013 39 tRNA (guanine) methyltransferase activity(GO:0016423) 17006, 509, 13, 1 2.57 0.467659351308 0.822090582663 13 aminoacyl-tRNA ligase activity(GO:0004812) 17006, 1897, 41, 11 2.405 0.0243870144655 0.283286111312 41 nuclear receptor activity(GO:0004879) 17006, 92, 46, 1 4.018 0.510687257922 0.844743089721 46 tRNA-specific ribonuclease activity(GO:0004549) 17006, 1663, 16, 3 1.917 0.369180472294 0.78957231445 16 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016893) 17006, 1663, 39, 5 1.311 0.622117571892 0.891403190854 39 protein disulfide oxidoreductase activity(GO:0015035) 17006, 847, 24, 1 0.837 0.822016670497 0.95528545717 24 peptide disulfide oxidoreductase activity(GO:0015037) 17006, 1528, 15, 3 2.226 0.292465011214 0.735062494398 15 protein serine/threonine phosphatase inhibitor activity(GO:0004865) 17006, 1111, 11, 3 4.175 0.0876166596798 0.48660220134 11