Cistrome-GO is a webserver for functional enrichment analysis of transcription factor binding sites. It has two working modes. If the user provides both a TF’s ChIP-seq peak file and a differential expression analysis file (upon the TF’s perturbation), Cistrome-GO will perform an ensemble mode analysis based on the integration of the two types of data. If the user uploads only a TF ChIP-seq peak file, Cistrome-GO will perform the analysis in solo mode. You can click to run an example or download an example bed file. Check demo for more examples.